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Federal University of São Paulo tested an interdisciplinary approach merging clinical, nutritional, psychological, and exercise counseling through remote and in-person sessions as published in the International Journal of Environmental Research and Public Health (1 ✔). These two achievements led to reduced insulin resistance and hence a lower risk of diabetes, as well as less visceral fat and a better energy balance (the ratio of calorie intake to calorie expenditure). All these [...]

Rats exposed to high fructose intake show early disruptions in the autonomic nervous, cardiovascular, and metabolic systems, elevating the risk of adult chronic diseases like diabetes and obesity, as per a study by Brazilian scientists. The findings are published in the International Journal of Obesity. The findings confirm information in the scientific literature regarding the appearance of metabolic disorders such as high levels of triglycerides (150 mg/dL or more) and insulin resistance in [...]

In a Journal of Pediatrics article, Brazilian researchers detail a challenging diagnosis in a nine-year-old boy. Exome sequencing revealed mutations in GCK and BCL11B, leading to the rare conditions of monogenic diabetes and T-cell abnormality syndrome. This precise diagnosis significantly influenced treatment choices for the complex array of symptoms, including short stature, dental enamel hypoplasia, mental deficiency, speech delay, asthma, altered blood sugar, and recurring infections in [...]

Scientific literature emphasizes the pivotal role of CD4+ T cells in responding to lung infections. Yet, a Cell Reports article reveals that an imbalance in these defense cells across lung regions during infection can be detrimental in tuberculosis condition. () The study described in the article involved infecting mice with hypervirulent tuberculosis and influenza. This finding opens up perspectives for therapeutic interventions aimed at combating diseases that attack the lungs, while not [...]

Individuals with a prior Zika infection faced a 2.34 times increased risk of severe dengue and a 3.39 times higher likelihood of hospitalization compared to controls (those with no history of dengue or Zika). Relatively advanced age (over 59) was also a higher risk factor for severe forms of dengue and hospitalization, revealed the study published in the journal PLOS Neglected Tropical Diseases. "Our findings confirmed the results of a previous study involving children who had zika in [...]

Children born to women to undernourished pregnant women often face an increased risk of prostate cancer in adult life, according to two mice studies published in Scientific Reports (1 ✔). Protein-Poor Diet in Pregnancy Linked to Prostate Cancer Risk Among Kids in Adult Stage In the first study, researchers at Sao Paulo State University (UNESP) in Brazil detected alterations in gene expression that may have been associated with the hormone imbalance observed in the rats’ offspring [...]

  In women with hypertension, 30 minutes of physical activity yields significant benefits, correlating with a 14% lower risk of stroke, 9% lower risk of coronary artery disease death, and 7% lower risk of all-cause death, stated study.Rheumatoid arthritis is an autoimmune inflammatory disease affecting synovial joints and causing pain, swelling, and progressive physical incapacity. People with rheumatoid arthritis also tend to have high blood pressure, and previous [...]

A novel peptide called Bc-7a from the venom of snakes - pit viper Cotiara and South American bushmaster was found to lower blood pressure by inhibiting the activity of angiotensin-converting enzyme, reveals a study published in Biochimie (). Novel Peptide from Snake Venom Can Reduce Blood Pressure Brazilian snake and spider venoms continue to be a source of new discoveries with biotechnological potential. Two studies supported by FAPESP and recently published show how this is possible [...]

Growth hormone (GH) plays a pivotal role in various body tissues, contributing to bone and muscle development alongside other functions. Additionally, it serves as a potent anxiety reliever. A University of São Paulo (USP) study delved into GH's role in reducing anxiety, pinpointing the specific neuron population responsible for moderating GH's impact on neuropsychiatric conditions like anxiety, depression, and post-traumatic stress, providing deeper insights. An article on the [...]