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A new material with antifungal and antitumor properties has been developed by researchers at the Center for Development of Functional Materials (CDMF), one of the Research, Innovation and Dissemination Centers (RIDCs) supported by São Paulo Research Foundation - FAPESP. CDMF is hosted by the Federal University of São Carlos (UFSCar) in São Paulo State, Brazil. The compound was obtained from a sample of pure silver tungstate (a-Ag2WO4) irradiated with electrons and laser [...]

Brazilian researchers believe they have identified in patients treated at the University Hospital (HU) in Aracaju, state of Sergipe, a new species of parasite that can cause a disease similar to visceral leishmaniasis but is resistant to the treatments currently available. At least one person has died from complications associated with infection by the parasite. Results of the research, supported by São Paulo Research Foundation - FAPESP, were published September 30th in the journal [...]

Researchers based in Brazil, the United States and Germany have discovered that 12-HEPE, a lipid produced in response to cold by brown adipose tissue in the human body, helps reduce blood sugar. The results of their experiments with mice pave the way for new treatments for diabetes. The group also observed that a drug used to treat urinary dysfunction increases the amount of 12-HEPE released into the bloodstream in human patients. The study is published in Cell Metabolism. Its first author is [...]

There are many fungi that live in the body that make up the normal body microbial flora. One type, Candida, a type of yeast, normally thrives in small amounts in areas such as the skin, abdomen, and mouth, without causing any problem. But, when the body’s environment is altered, the yeast can uncontrollably proliferate and cause disease. Candidiasis is a fungal infection caused by yeast, with Candida albicans as the predominant cause of the illness. If it develops in the throat or mouth, [...]

The effects of more than 60 minutes of moderate daily physical exercise, such as walking, accumulate throughout life and are associated with a 39% reduction in the risk of advanced adenomatous polyps, a precursor of colorectal cancer, the third most frequent type of cancer in Brazil. This is the main finding of an epidemiological study published in the British Journal of Cancer. The study was conducted by researchers in the Department of Preventive Medicine at the University of São [...]

Approximately ten out of every 100 people who are bitten by mosquitos infected by the yellow fever virus develop symptoms of the disease. Although most infected people do not develop the disease, it is lethal to approximately 40% of those who do. Outbreaks of yellow fever have occurred in Brazil in recent years despite the existence of a safe and efficacious vaccine since 1938. Even after more than a century of research, scientists and physicians were unaware of any specific clinical and [...]

Corn starch, an abundant, cheap and biodegradable raw material, is the basis for a novel larvicide developed by researchers at the University of Campinas (UNICAMP) in São Paulo State, Brazil. The material is used in microcapsules for storage and controlled release of active compounds to kill larvae of Aedes aegypti, the mosquito that transmits dengue, zika, yellow fever and chikungunya. A patent application has been filed via UNICAMP's innovation agency (Inova). The methodology is [...]

The incidence of thyroid cancer among first responders who volunteered or were employed as firefighters, rescue personnel and cleanup workers at Ground Zero in New York on or after September 11, 2001, is three times higher than that in the general population. This difference has been confirmed by a method involving a panel of four biomarkers that distinguish benign from malignant thyroid cancer cases on the basis of gene expression. The tests were developed by researchers at the Federal [...]

Evaluating body composition, especially appendicular muscle mass, can be an effective strategy for predicting longevity in people over 65 years of age, according to a study conducted by researchers at the University of São Paulo's Medical School (FM-USP) in Brazil. The appendicular muscles are the muscles that move the appendages or extremities – the arms and legs. They also play a key role in stabilizing the shoulders and hips. The researchers studied a group of 839 men and [...]