Veículo
News Medical (Austrália)
Em 2022: 30 notícias
Desde 1995: 295 notícias
New studies improve understanding of the genetic factors that protect people against COVID-19
Publicado em 22 novembro 2022
Two recent papers by Brazilian researchers have contributed to the scientific understanding of the genetic factors that protect people against infection by SARS-CoV-2 or prevent progression to severe COVID-19. One reports the results of a study involving a group of resilient older people aged 90 or more, and the other analyzes a case of severe COVID-19 in identical twins, only one of whom suffered from long-term symptoms of the disease.
Since 2020, researchers in several countries, including [...]
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Study highlights the importance of poverty in criminal conviction
Publicado em 02 novembro 2022A significant reduction in childhood poverty could cut criminal convictions by almost a quarter, according to a study conducted in Brazil. An article on the study is published in Scientific Reports. The researchers used an innovative approach involving an analysis of 22 risk factors that affect human development and interviews with 1,905 children at two points – a first interview to form a baseline (mean age 10.3) and a follow-up interview seven years later (mean age 17.8). The [...]ver notícia -
Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19
Publicado em 28 outubro 2022An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of severe COVID-19. The creators of this therapy, which can successfully activate the immune system to fight cancer, won the 2018 Nobel Prize in Physiology or Medicine. The findings reported by the authors were based on experiments involving cells from patients treated in intensive care units (ICUs) after being infected by SARS-CoV-2, and [...]ver notícia -
Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research
Publicado em 21 outubro 2022Experiments involving animals and human cells conducted at the University of São Paulo (USP) in Brazil suggest that niclosamide, an anthelmintic widely used against tapeworms, effectively inhibits SARS-CoV-2 replication as well as the exacerbated inflammatory response that leads to death in many patients with severe COVID-19. More research is needed to find out whether the effects, described in an article published in Science Advances, are confirmed in patients with the disease, and [...]ver notícia -
Study offers new insights into other melanomas not caused by the effects of UV radiation
Publicado em 11 outubro 2022A group of researchers based in Brazil and France have managed to discover markers left by exposure to sunlight in the genomes of people who suffer from cutaneous melanoma. An article about the study published in Nature Communications also offers a novel understanding of other melanomas not caused by the effects of ultraviolet (UV) radiation. We found some of the alterations to be markers of the patient's survival. We were able to predict whether a person was more or less likely to [...]ver notícia -
Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon
Publicado em 06 outubro 2022Testing on humans of a novel COVID-19 vaccine developed in Brazil will begin this year. It performed well in animal trials, as reported in an article published in August in Nature Communications. The scientists responsible for the vaccine have just received authorization from the National Health Surveillance Agency (ANVISA) to begin clinical trials. “There are only some minor adjustments left to be made in the study’s protocol before we submit it once again to the approval of the [...]ver notícia -
Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system
Publicado em 30 setembro 2022A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system. A preliminary version (not yet peer-reviewed) posted in 2020 was one of the first to show that the virus that causes COVID-19 can infect brain cells, especially astrocytes. It also broke new ground by describing alterations in the structure of the cortex, the most neuron-rich brain region, even in cases of mild COVID-19. The cerebral cortex is the [...]ver notícia -
Cutting protein intake can help control obesity, diabetes and hypertension
Publicado em 20 setembro 2022Cutting protein intake can help control metabolic syndrome and some of its main symptoms, such as obesity, diabetes and high blood pressure (hypertension), according to a study conducted by researchers in Brazil and Denmark to compare the effects of protein and calorie restriction diets in humans. An article reporting the study is published in the journal Nutrients. Metabolic syndrome is a cluster of conditions that heighten the risk of cardiovascular disease, stroke and diabetes, including [...]ver notícia -
Hyperglycemia has the most significant impact on cardiovascular disease mortality
Publicado em 20 setembro 2022Several factors increase the risk of heart attack, such as high blood sugar (hyperglycemia), obesity, abnormal cholesterol levels, high blood pressure (hypertension), and smoking. A study conducted in Brazil and reported in an article published in the journal PLOS ONE measured the impact of these factors. The researchers analyzed data for the Brazilian population collected between 2005 and 2017, determining the number of deaths attributed to each risk factor. The aim of the study was to [...]ver notícia -
Novel antifungal medications urgently needed to control COVID-19-associated fungal infections
Publicado em 09 setembro 2022Every day we inhale thousands of potentially pathogenic fungal spores, but our immune system simply eliminates them. However, in people with compromised immunity, such as transplant and cancer patients, as well as hospitalized patients in intensive care, the interaction between pathogen and host may be quite different. Fungal infections that emerged during the COVID-19 pandemic, reinforcing the action of SARS-CoV-2 around the world, are a case in point. Mortality reached 80% among severe [...]ver notícia