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Brazilian scientists at São Paulo State University (UNESP) collaborating with colleagues at the University of Maryland and the US Department of Agriculture (USDA) have developed a dairy cattle breeding method that adds a new parameter to genetic selection and conserves or even improves a population’s genetic diversity, writes André Julião, Agência FAPESP. The study, which is published in Journal of Dairy Science, was funded by the São Paulo Research [...]

Dresden, Germany — An international group of researchers has proven that a molecule called TCMDC-135051 can selectively inhibit a protein that is essential to the lifecycle of Plasmodium falciparum, one of the parasites that causes malaria. The results of the study, just published in the journal Science, pave the way for the development of a new antimalarial drug. Malaria kills nearly 500,000 people per year, and more than 200 million new cases of the disease are reported annually. One [...]

Ever since three U.S.-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other conditions. The Nobel Prize in Physiology or Medicine in 1998 was awarded jointly to Robert F. Furchgott, Louis J. Ignarro and Ferid Murad for groundbreaking research of nitric oxide [...]

An international group of researchers has proven that a molecule called TCMDC-135051 can selectively inhibit a protein that is essential to the lifecycle of Plasmodium falciparum, one of the parasites that causes malaria. The results of the study, just published in the journal Science, pave the way for the development of a new antimalarial drug. Malaria kills nearly 500,000 people per year, and more than 200 million new cases of the disease are reported annually. One of the obstacles to [...]

São Paulo, Brazil — Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other conditions. The Nobel Prize in Physiology or Medicine in 1998 was awarded jointly to Robert F. Furchgott, Louis J. Ignarro and Ferid Murad for [...]

Oxide plays a key role in cardiovascular and neurodegenerative diseases as well as cancer; experiments reveal a hitherto unknown mechanism underlying the formation of nitroso thiols Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other [...]

Oxide plays a key role in cardiovascular and neurodegenerative diseases as well as cancer; experiments reveal a hitherto unknown mechanism underlying the formation of nitroso thiols Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other [...]

A new material with antifungal and antitumor properties has been developed by researchers at the Center for Development of Functional Materials (CDMF), one of the Research, Innovation and Dissemination Centers (RIDCs) supported by São Paulo Research Foundation – FAPESP. CDMF is hosted by the Federal University of São Carlos (UFSCar) in São Paulo State, Brazil. The compound was obtained from a sample of pure silver tungstate (a-Ag2WO4) irradiated with electrons and [...]

A new material with antifungal and antitumor properties has been developed by researchers at the Center for Development of Functional Materials (CDMF), one of the Research, Innovation and Dissemination Centers (RIDCs) supported by São Paulo Research Foundation – FAPESP. CDMF is hosted by the Federal University of São Carlos (UFSCar) in São Paulo State, Brazil. The compound was obtained from a sample of pure silver tungstate (a-Ag2WO4) irradiated with electrons and [...]