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Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids

Publicado em 03 maio 2022
In a study published May 02, 2022 in Nature Communications, scientists at University of California San Diego School of Medicine used human brain organoids to reveal how a genetic mutation associated with a profound form of autism disrupts neural development. Using gene therapy tools to recover the gene’s function effectively rescued neural structure and function. Several neurological and neuropsychiatric diseases, including autism spectrum disorders (ASD) and schizophrenia have been [...]