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Peptides are biomolecules formed when two or more amino acids that perform key functions in the human organism, such as hormones, neurotransmitters, painkillers and antibiotics, bind together. For this reason, they are much studied and used by the pharmaceutical industry, for example. A study conducted by scientists in the Department of Biophysics at the Federal University of São Paulo's Medical School (EPM-UNIFESP) in Brazil identified significant changes in the physicochemical [...]

The incidence of thyroid cancer in São Paulo State, part of Brazil's relatively developed Southeast region, varies considerably according to socioeconomic status (education, poverty, wealth, income, segregation, mobility, and access to resources and services) and access to screening, but is highest in higher-income areas and the state capital. Mortality rates are similar across regions and income groups, however. These are the main findings of a study reported in the journal [...]

Researchers in São Paulo state, Brazil, have developed a low-cost anti-inflammatory hydrogel that in future could help treat chronic skin lesions such as those often seen in people with diabetes. They report the results of animal tests in an article published in the journal Biomedicine & Pharmacotherapy. According to the International Diabetes Federation, Brazil ranks sixth among countries with the most cases of diabetes, which has reached epidemic proportions and become the fifth [...]

Fundação de Amparo à Pesquisa do Estado de São Paulo Researchers in São Paulo state, Brazil, have developed a low-cost anti-inflammatory hydrogel that in future could help treat chronic skin lesions such as those often seen in people with diabetes. They report the results of animal tests in an article published in the journal Biomedicine & Pharmacotherapy. According to the International Diabetes Federation, Brazil ranks sixth among countries with the [...]

The presence of Indigenous communities and traditional river dwellers in extractive reserves located in Legal Amazonia is not a threat to birds and mammals considered subsistence poaching targets, according to a study reported in the journal Biological Conservation. Legal Amazonia is an area of more than 5 million square kilometers comprising the Brazilian states of Acre, Amapá, Amazonas, Maranhão, Mato Grosso, Pará, Rondônia, Roraima, and Tocantins. It was created [...]

A digital map of flood-prone areas in Brazilian cities São Paulo and Rio Branco created by public school students; a history of floods recorded in a poor neighborhood of São Paulo based on the residents' recollections; new communication channels with the Civil Defense authorities to improve the early warning system – these are some of the instruments for citizen participation and mobilization shown to be effective in initiatives to increase survival of urban [...]

Mice that were infected with zika virus during pregnancy and developed microcephaly displayed less activity of Ndel1, an enzyme that plays a key role in neuron proliferation, differentiation and migration during embryo development, according to an article published in the Journal of Neurochemistry. The discovery has been patented and could serve in future as a basis for the development of a biomarker for early diagnosis of microcephaly in human babies infected with zika during the embryonic [...]

In an article published in the journal Flora, researchers at São Paulo State University (UNESP) in Brazil examine some of the strategies developed over eons of evolution by plants in the Cerrado, Brazil's savanna-like biome, to protect themselves and resprout quickly after fire. The article is commended by the journal as Highlighted Student Research. Its first author, Marco Antonio Chiminazzo, a PhD candidate at UNESP in Rio Claro, received funding from FAPESP for his master's [...]

Polyalthic acid from copaiba oil is an effective antibacterial and should be used to develop alternative medications that can contribute to the effort to overcome antimicrobial resistance (“superbugs”), according to an article by researchers based in Brazil and the United States published in the journal Antibiotics. More than 2.8 million antibiotic-resistant infections occur in the US and more than 35,000 people die as a result each year, says a report issued in 2019 by the [...]