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An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of seve Newswise — re COVID-19. The creators of this therapy, which can successfully activate the immune system to fight cancer, won the 2018 Nobel Prize in Physiology or Medicine. The findings reported by the authors were based on experiments involving cells from patients treated in intensive care units (ICUs) after being infected [...]

Des expériences impliquant des animaux et des cellules humaines menées à l'Université de São Paulo (USP) au Brésil suggèrent que la niclosamide, un anthelminthique largement utilisé contre les ténias, inhibe efficacement la réplication du SRAS-CoV-2 ainsi que la réponse inflammatoire exacerbée qui conduit à la mort chez de nombreux patients atteints de COVID-19 sévère. Des recherches [...]

Sarcopenia, a clinical syndrome characterized by progressive and extensive decline in skeletal muscle mass, force and function, is widely considered part of aging. Early diagnosis is extremely important and begins with handgrip measurement using a dynamometer. A recent study by researchers at the Federal University of São Carlos (UFSCar) in São Paulo state, Brazil, collaborating with colleagues at University College London (UCL) in the United Kingdom, concluded that the [...]

A technique developed by Brazilian researchers enhances the efficiency of breeding programs, saving selection time and the cost of plant genotyping and characterization A Brazilian study published in Scientific Reports shows that artificial intelligence (AI) can be used to create efficient models for genomic selection of sugarcane and forage grass varieties and predict their performance in the field on the basis of their DNA. In terms of accuracy compared with traditional breeding [...]

Spin is the intrinsic magnetic moment of a particle—an electron, for example. It is a fundamental magnitude, like mass and charge. Simply put, it is as if the particle had a magnet inside it that enabled it to interact, even while at rest, not only with the spins of other particles but also with external magnetic fields. Honeycomb lattice with two impurities located in the center of the areas shaded blue. Credit: Eric Andrade/USPBy analogy with usual liquids, a system in which spins do [...]

An article about the study published in Nature Communications also offers a novel understanding of other melanomas not caused by the effects of ultraviolet (UV) radiation. We found some of the alterations to be markers of the patient's survival. We were able to predict whether a person was more or less likely to survive thanks to these markers present in their DNA." Anna Luiza Silva Almeida Vicente, First Author The study was conducted during her PhD research at Hospital de Amor, [...]

Cette étude basée sur l'imagerie de cerveau de patients atteints de COVID-19 légers, sur l'analyse de tissus cérébraux de personnes décédées de la maladie et sur des expériences in vitro menées sur des cellules nerveuses humaines infectées en laboratoire, révèle, pour la première fois, la cible principale du SRAS-CoV-2 dans le cerveau, les astrcytes. La recherche décrit [...]

A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system. A preliminary version (not yet peer-reviewed) posted in 2020 was one of the first to show that the virus that causes COVID-19 can infect brain cells, especially astrocytes. It also broke new ground by describing alterations in the structure of the cortex, the most neuron-rich brain region, even in cases of mild COVID-19. The cerebral cortex is the [...]

Newswise — A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system. A preliminary version (not yet peer-reviewed) posted in 2020 was one of the first to show that the virus that causes COVID-19 can infect brain cells, especially astrocytes. It also broke new ground by describing alterations in the structure of the cortex, the most neuron-rich brain region, even in cases of mild COVID-19. The cerebral [...]