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Biomarkers that could help determine who's at risk for severe COVID-19 symptoms
Publicado em 10 de fevereiro de 2021
One of the many mysteries still surrounding COVID-19 is why some people experience only mild, flu-like symptoms, whereas others suffer life-threatening respiratory problems, vascular dysfunction and tissue damage. Now, researchers reporting in ACS' Analytical Chemistry have used a combination of metabolomics and machine learning to identify possible biomarkers that could both help diagnose COVID-19 and assess the risk of developing severe illness.
Although some pre-existing conditions, [...]
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Lung ultrasound helps predict COVID-19 patient outcomes
Publicado em 10 fevereiro 2021Lung ultrasound, considered a simple method for diagnosing lung disease, can also help predict the clinical progression of severe COVID-19 patients, according to a study conducted at the University of São Paulo's Medical School (FM-USP) in São Paulo City, Brazil. The principal investigator for the study was Heraldo Possolo de Souza, a professor at FM-USP and an attending physician at its teaching and general hospital, Hospital das Clínicas (HC). The researchers [...]ver notícia -
Studies use mathematics to analyze the semantics of dream reports during the pandemic
Publicado em 04 fevereiro 2021The COVID-19 pandemic has affected people's behavior everywhere. Fear, apprehensiveness, sadness, anxiety, and other troublesome feelings have become part of the daily lives of many families since the first cases of the disease were officially recorded early last year. These turbulent feelings are often expressed in dreams reflecting a heavier burden of mental suffering, fear of contamination, stress caused by social distancing, and lack of physical contact with others. In addition, dream [...]ver notícia -
Researchers develop 10-minute COVID-19 diagnostic test that wage workers can afford
Publicado em 02 fevereiro 2021A test that detects antibodies to the novel coronavirus in 10 minutes and costs only a fifth of the market average has been developed by researchers at the University of São Paulo's São Carlos Chemistry Institute (IQSC-USP) and Brazilian startup Biolinker, with São Paulo Research Foundation - FAPESP's support. The device works similarly to the rapid tests available now in pharmacies. It analyzes a drop of blood, and two red LEDs light up if it detects the presence [...]ver notícia -
Why it is harder for Brazilians of African descent to find bone marrow donors
Publicado em 02 fevereiro 2021A paper by a multidisciplinary team of scientists affiliated with various Brazilian institutions, including the University of São Paulo (USP) and the National Cancer Institute (INCA), shows that people of African descent are less likely to find a donor in the National Register of Voluntary Bone Marrow Donors (REDOME) than people with predominantly European ancestry. The paper is published in Frontiers in Immunology. REDOME is the world’s third-largest bone marrow bank, with more [...]ver notícia -
Startup develops yeast-based COVID-19 diagnostic test
Publicado em 29 janeiro 2021Incubated at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, and supported by São Paulo Research Foundation- FAPESP's Innovative Research in Small Business Program (PIPE), BIOinFOOD is a startup that is developing a rapid COVID-19 diagnostic test based on a patent application filed by students at UNICAMP's Genomics and Bioenergy Laboratory. The test is based on a biosensor consisting of a genetically modified brewer's yeast (Saccharomyces [...]ver notícia -
Melatonin produced in the lungs prevents infection by novel coronavirus
Publicado em 27 janeiro 2021Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus. The hormone, therefore, prevents infection of these cells by the virus and inhibits the immune response so that the virus remains in the respiratory tract for a few days, eventually leaving to find another [...]ver notícia -
A quarter of known bee species haven't appeared in public records since the 1990s
Publicado em 23 janeiro 2021Researchers at the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) in Argentina have found that, since the 1990s, up to 25% of reported bee species are no longer being reported in global records, despite a large increase in the number of records available. While this does not mean that these species are all extinct, it might indicate that these species have become rare enough that no one is observing them in nature. The findings appear January 22 in the [...]ver notícia -
Researchers at Brazil's space institute discover why lightning branches and flickers
Publicado em 13 janeiro 2021Researchers at Brazil's National Space Research Institute (INPE), in partnership with colleagues in the United States, United Kingdom and South Africa, have recorded for the first time the formation and branching of luminous structures by lightning strikes. Analyzing images captured by a super slow motion camera, they discovered why lightning strikes bifurcate and sometimes then form luminous structures interpreted by the human eye as flickers. The study was supported by São Paulo [...]ver notícia -
Scientists study use of abundant enzyme in tumor cells to monitor cancer treatment
Publicado em 12 janeiro 2021The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential. It is also known to perform important functions in cells under normal conditions, participating in both the proliferation process and the regulation of intracellular systems. Research continues on its role in cancer progression. In Brazil, a group of researchers at the University of [...]ver notícia