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In an article published in the journal eLife, researchers at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, describe a novel strategy for detecting imbalances and complications in patients infected by Plasmodium vivax, one of the parasites that causes malaria and the main cause of the disease in the Americas. According to the study, total parasite biomass in the patient is a better predictor of the extent of infection outside the bloodstream than parasitemia, [...]

A Brazilian study described in an article published in the journal Salamandra evidences the versatility of amphibians in terms of reproductive modes: their eggs and larvae can develop in at least 74 different ways. Signed by scientists at the University of Campinas (UNICAMP) and São Paulo State University (UNESP) in Brazil, the article compiles data available in the specialized literature and collected by the authors over decades of research. In addition, it proposes [...]

(Reuters) – The following is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that have yet to be certified by peer review. Coronavirus transforms pancreas cell function When the coronavirus infects cells, it not only impairs their activity but can also change their function, new findings suggest. For example, when insulin-producing beta cells in the pancreas become infected with the virus, they not only [...]

Sao Paulo [Brazil], September 1 (ANI): A new study has found that the dangerous combination of weak muscles and abdominal fat can lead to a significant loss of gait speed in older people. The findings of the study were published in the journal 'Age and Ageing'. The study was conducted by researchers at the Federal University of Sao Carlos (UFSCar) in the state of Sao Paulo, Brazil, in partnership with colleagues at University College London (UCL) in the UK. A slower gait is a natural [...]

Aging entails a loss of muscle mass and strength, which in some cases impairs mobility, hinders walking or performance of day-to-day tasks, and exposes the elderly to the risk of falls and hospitalizations. In clinical practice, handgrip measurement is the most widely used method to identify loss of overall muscular strength in older people. Values below 26 kg for men and 16 kg for women have for some time been considered an indication of risk-associated weakness, but these parameters are [...]

Researchers at the Human Genome and Stem Cell Research Center (HUG-CELL), hosted by the University of São Paulo’s Institute of Biosciences (IB-USP) in Brazil, have developed a technique to reconstruct and produce livers in the laboratory. The proof-of-concept study was conducted with rat livers. In the next stage of their research, the scientists will adapt the technique for the production of human livers in order in future to increase the supply of these organs for [...]

Scientists affiliated with the Center for Research on Inflammatory Diseases (CRID), hosted by the University of São Paulo (USP) in Brazil, have discovered that an enzyme involved in key metabolic processes also plays a role in immune cell differentiation and hence in the development of autoimmune diseases. The finding could contribute to the future development of new treatments and more cost-effective and resolutive medications for this kind of disease. The study is reported in the [...]

Zika virus infection during pregnancy can cause severe abnormalities in the fetus, including malformations such as microcephaly. In a small proportion of cases, the disease may lead to miscarriage and perinatal death. A network of more than 30 Brazilian researchers set out to find the causes of these problems with the support of FAPESP and obtained important results after half a decade of hard work. A paper describing their findings has been published in the journal Science [...]

Researchers at São Paulo State University (UNESP) in Araçatuba, Brazil, have developed a computational tool that acts like a "COVID-19 accelerometer," plotting in real time the rate at which growth is accelerating or decelerating in more than 200 countries and territories. Available free of charge online, the application automatically loads the most recently notified case numbers from the European Center for Disease Prevention and Control (ECDC), updated daily, and [...]