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 In a study conducted at the University of São Paulo’s Human Genome and Stem Cell Research Center (HUG-CELL) in Brazil, serial systemic injections of zika virus into mice with brain tumors destroyed the cancer without causing neurological damage or injuring other organs, and increased the animals’ survival rate. The scientists also injected zika into cerebral organoids, brain-like organs created in vitro using stem cells. The virus not only prevented progression of [...]

Which is the best COVID-19 vaccine? For the experts who participated in a webinar held by FAPESP, this question cannot be answered right now. The various vaccines approved and in use around the world were developed using different techniques and tested under different conditions, so the results of the respective Phase 3 clinical trials completed to date are simply not comparable. “It’s impossible to say if this or that vaccine confers more protection than another. They’ve [...]

Incubated at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, and supported by FAPESP’s Innovative Research in Small Business Program (PIPE), BIOinFOOD is a startup that is developing a rapid COVID-19 diagnostic test based on a patent application filed by students at UNICAMP’s Genomics and Bioenergy Laboratory. The test is based on a biosensor consisting of a genetically modified brewer’s yeast (Saccharomyces cerevisiae), which changes color if [...]

Researchers at Brazil’s National Space Research Institute (INPE), in partnership with colleagues in the United States, United Kingdom and South Africa, have recorded for the first time the formation and branching of luminous structures by lightning strikes. Analyzing images captured by a super slow motion camera, they discovered why lightning strikes bifurcate and sometimes then form luminous structures interpreted by the human eye as flickers. The study was supported by FAPESP. An [...]

A drug used to treat pulmonary hypertension significantly reduced the capacity of tumor cells to migrate and invade other tissues in trials involving pancreatic, ovarian, breast cancer, and leukemia cell lines. Furthermore, in mice with an aggressive form of breast cancer, the drug reduced the incidence of metastasis in the liver and lungs by 47% and lengthened survival compared with untreated animals. The study is published in Scientific Reports. Marques conducted the study [...]

By  – In Brazil, researchers at São Paulo State University (UNESP) in Ilha Solteira have developed a film that can replace plastic in food packaging. The film is made from hydroxypropyl methylcellulose (HPMC) and bacterial cellulose scraps left over from industrial processing. Both raw materials are sustainable. They are combined to produce a biodegradable film of bacterial cellulose nanocrystals and HPMC. The product outperforms film made of HPMC alone. An article on [...]

The product outperforms film made of HPMC alone.

By Elton Alisson | Agência FAPESP – It is already possible to produce food with a 3D printer, potentially delivering products that suit consumer preferences regarding taste, texture, cost, convenience, and nutrition. In the near future, it will be possible to produce food with personalized shapes, textures, flavors, and colors considered attractive and healthy for children and the elderly, for example. A group of researchers at the University of São Paulo’s Luiz de [...]

The hypothesis that blood clotting disorders may explain some of the worst symptoms of COVID-19, including respiratory failure and pulmonary fibrosis, was suggested in mid-April by researchers in Brazil affiliated with the University of São Paulo’s Medical School (FM-USP) via an article accepted for publication by the Journal of Thrombosis. In less than a month, the topic had been highlighted in articles posted to the websites of Science and Nature, both of which are among the [...]