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An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of severe COVID-19. The creators of this therapy, which can successfully activate the immune system to fight cancer, won the 2018 Nobel Prize in Physiology or Medicine. The findings reported by the authors were based on experiments involving cells from patients treated in intensive care units (ICUs) after being infected [...]

Join us in The Bullpen, where the members of the Scientific Inquirer community get to shape the site’s editorial decision making. We’ll be discussing people and companies to profile on the site. On Wednesday, October 26 at 5:30pm EST, join us on Discord and let’s build the best Scientific Inquirer possible. Sarcopenia, a clinical syndrome characterized by progressive and extensive decline in skeletal muscle mass, force and function, is widely considered part of aging. Early [...]

Researchers identify genes potentially responsible for sugarcane’s resistance to pests, cold and drought. Credit: Luciana Rossini/IAC, Sugarcane Center, Ribeirão Preto A study conducted at the State University of Campinas (UNICAMP) in Brazil has identified orphan genes in wild sugarcane (Saccharum spontaneum), a species with exceptional resistance to biotic stresses such as nematodes, fungi, bacteria and other pests and diseases, and abiotic stresses such as cold, drought, [...]

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate. In laboratory tests, the researchers inhibited interaction between the molecules using a drug and thereby reduced viral [...]

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom. They used a technique called PEGylation to make the molecule, now called PEG-rCollinein-1, more stable in the organism and resistant to the immune system, obtaining a drug candidate to modulate blood clotting. An article reporting the results of the research has recently been published in the International Journal of Biological [...]

A scientific expedition in the Javari River basin on the border between Brazil, Colombia and Peru has shown use of environmental DNA sequencing to be feasible to investigate fish diversity in the Amazon. The eDNA method consists of extracting molecules of DNA present in water samples and identifying the species to which they belong by means of genetic markers.  An article on the research published in the journal Scientific Reports also discusses the limitations of the [...]

Only well-adapted organisms can survive constant exposure to sunlight and temperature fluctuations during the day, not to mention scarcity of water. Researchers supported by FAPESP identified a group of bacteria and a yeast that have adapted to such conditions on photovoltaic panels, which convert sunlight into electricity. The panels are installed in Sorocaba and Itatiba, São Paulo state, Brazil. An article reporting the results of the research is published in the [...]

In 2019, history student Rodrigo Gomes found out on social media about a call for volunteers to take part in a scientific project relating to the ocean and conducted by the Federal University of São Paulo’s Institute of Marine Sciences (IMAR-UNIFESP) in Santos, on the coast of the state of São Paulo, Brazil. He signed up for the project, took workshops, and trained in the field. “I was very fortunate to have all that contact with professors and learned a great deal [...]

In 2019, history student Rodrigo Gomes found out on social media about a call for volunteers to take part in a scientific project relating to the ocean and conducted by the Federal University of São Paulo’s Institute of Marine Sciences (IMAR-UNIFESP) in Santos, on the coast of the state of São Paulo, Brazil. He signed up for the project, took workshops, and trained in the field. “I was very fortunate to have all that contact with professors and learned a great deal [...]