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The first human-tested weight-loss drug that burns calories through creatine-based heat generation, without reducing appetite, has successfully completed its Phase I trial. Scientists from the Institut Pasteur de Montevideo (IP Montevideo) and the University of the Republic (Udelar) have built on their promising preclinical mouse study to demonstrate that SANA, a small molecule drug that harnesses an unexplored fat-burning pathway, is not only safe for human use but effective. SANA is a [...]

he accelerated degradation of the Brazilian Amazon, primarily due to fires, has overshadowed the significant reduction in deforestation from 2022 to 2024. This "negative balance" in protecting the biome jeopardizes the international goals for combating the climate crisis that have been assumed by the country, which is hosting the United Nations Climate Change Conference (COP30) this year. This warning comes from an article in the journal Global Change [...]

A study conducted by researchers from the University of São Paulo (USP) in Brazil has revealed the structure of the so-called "blue economy" in the country – the set of economic activities that depend directly on marine resources. Using an interregional input-output model, the researchers mapped the direct and indirect impacts of these activities. This highlighted the economic importance of the coast and its deep connection with the country's interior. The [...]

The accelerated degradation of the Brazilian Amazon, primarily due to fires, has overshadowed the significant reduction in deforestation from 2022 to 2024. This "negative balance" in protecting the biome jeopardizes the international goals for combating the climate crisis that have been assumed by the country, which is hosting the United Nations Climate Change Conference (COP30) this year. This warning comes from an article in the journal Global Change [...]

The Brazilian Amazon has witnessed a staggering increase in forest degradation, rising by 163% over the past two years, according to recent research. This alarming trend comes despite a significant reduction in deforestation rates, which fell by 54% during the same period. The findings, published in Global Change Biology, highlight a troubling “negative balance” in efforts to protect this vital ecosystem, especially as Brazil prepares to host the United Nations Climate Change Conference [...]

New research from scientists in Brazil is shedding light on the long-standing mystery of why saber-toothed tigers went extinct. According to two new studies from the State University of Campinas (UNICAMP), the answer may lie in the complex relationship between predators and their prey over millions of years. Saber-toothed tigers, known for their huge, curved canine teeth, were once fearsome predators of large animals across North America and Eurasia. For years, scientists believed [...]

A group supported by FAPESP and led by University of São Paulo (USP) researchers in Brazil has described a new genus of frogs, Dryadobates , also known as rocket frogs, which was previously considered a single species. The study was published in the Bulletin of the American Museum of Natural History. The researchers used techniques that allow the analysis of degraded DNA obtained from specimens preserved in alcohol or formalin and deposited in natural history collections. [...]

A study conducted by researchers at the University of São Paulo (USP) in Brazil and the Università degli Studi di Roma "La Sapienza" in Italy has synthesized fullerenes and hollow spherical graphene particles using only natural graphite, ethanol, water, and sodium hydroxide under ambient conditions. Published in the journal Diamond and Related Materials, the research showed the feasibility of producing structures that previously required extremely high [...]

As cancer cases have increased worldwide, the disease has become more complex, presenting challenges to scientific advances in diagnosis and treatment. In this context, artificial intelligence (AI) has emerged as a valuable tool for predicting and detecting cases. A tool developed by Brazilian and Polish researchers may contribute to this process. The machine learning model can predict the aggressiveness of certain tumors by identifying specific proteins. It generates a stemness index [...]