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Vaccination has changed the profile of hospitalized COVID-19 patients and people who die from the disease in Brazil. A study conducted in São José do Rio Preto, in the state of São Paulo, Brazil, reports on the start of this process. Researchers affiliated with the Virology Laboratory at São José do Rio Preto Medical School (FAMERP) retrospectively analyzed data for 2,777 patients treated between January 5 and September 12, 2021, at the region’s base [...]

At least ten out of every 100 girls older than the appropriate age for their school grade could have accompanied their age group if mental health problems were prevented or treated, especially externalizing disorders (problematic behavior relating to poor impulse control, such as attention deficit and hyperactivity, aggression, impulsivity, and rule-breaking). Among children in the Brazilian public education system, data on the incidence of mental health problems are also reflected by grade [...]

In an article published in the journal eLife, researchers at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, describe a novel strategy for detecting imbalances and complications in patients infected by Plasmodium vivax, one of the parasites that causes malaria and the main cause of the disease in the Americas. According to the study, total parasite biomass in the patient is a better predictor of the extent of infection outside the bloodstream than parasitemia, [...]

Yellow fever is a non-contagious viral disease with two transmission cycles, sylvatic (in wild animals) and urban. Sylvatic yellow fever circulates among monkeys, and in Brazil is transmitted by mosquitoes of the genera Haemagogus and Sabethes, which bite an infected monkey and then infect others. Urban yellow fever circulates among humans and is transmitted by the mosquito Aedes aegypti (human-mosquito-human). Brazil has had no urban yellow fever cases since 1942, but the sylvatic version can [...]

Torquetenovirus (TTV) is one of the viruses most frequently found in the human organism. It is also common in monkeys and domestic animals. Its presence has not been associated with any known disease, but its excessive replication is a sign that something is wrong with the immune system. The correlation between high TTV load and immunosuppression has been used in medicine in certain contexts, such as monitoring transplant patients who take medication to prevent rejection of the transplanted [...]

A review article published in the journal Frontiers in Physiology by researchers affiliated with the Federal University of São Paulo (UNIFESP) in Brazil discusses the mechanisms whereby SARS-CoV-2 damages the kidneys, potentially serving as a basis for further research in pursuit of treatments to prevent severe renal problems and even chronic kidney disease in COVID-19 patients. The study shows that interaction with angiotensin-converting enzyme 2 (ACE2) not only enables the virus to [...]

Researchers at the University of São Paulo (USP) in Brazil have shown that a hypertonic saline solution inhibits replication of SARS-CoV-2, the virus that causes COVID-19, and have elucidated the biochemical mechanism involved. An article reporting the research is published in ACS Pharmacology & Translational Science. The study was performed in the laboratory using human epithelial lung cells infected with the virus. If the strategy proves effective in clinical trials, it [...]

Sao Paulo [Brazil], September 1 (ANI): A new study has found that the dangerous combination of weak muscles and abdominal fat can lead to a significant loss of gait speed in older people. The findings of the study were published in the journal 'Age and Ageing'. The study was conducted by researchers at the Federal University of Sao Carlos (UFSCar) in the state of Sao Paulo, Brazil, in partnership with colleagues at University College London (UCL) in the UK. A slower gait is a natural [...]

Brasilia [Brazil], August 25 (ANI): Transcranial direct current stimulation (tDCS) can increase the benefits of aerobic exercise and improve the gait of patients with Parkinson's disease immediately after a session. Step time variability decreases, reaction time shortens, and executive control of gait is enhanced. These were the main findings of a randomized, double-blinded, sham-controlled crossover study of 20 volunteers by researchers at Sao Paulo State University's Institute of [...]