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A recent meta-analysis found that glutamatergic medications may effectively treat obsessive-compulsive and related disorders (OCRDs), particularly obsessive-compulsive disorder (OCD). The analysis included 27 trials and showed significant symptom improvement compared to control groups. The study highlighted that while standard treatments like SSRIs work for many, about 60% of OCD patients do not respond adequately. Glutamatergic medications, which affect brain signaling, could offer new [...]

A new study in Brazil has identified genetic links to pancreatic cancer, a disease recently added to the National Cancer Institute's statistics. Researchers analyzed 192 patients and found that 6.25% had hereditary mutations linked to the disease. The study is notable for its diverse sample, representing various regions of Brazil. It also discovered mutations in genes not previously associated with pancreatic cancer, highlighting the need for further research on these [...]

Summary: A study warns that up to 50% of the Amazon rainforest could reach a tipping point by 2050 due to water stress, land clearance, and climate disruption. The forest has already passed a safe boundary, with 15% cleared and 17% degraded. By 2050, 10-47% of the forest could face compounding disturbances. To prevent collapse, deforestation should be limited to 10% and global heating to 1.5C above pre-industrial levels. The Amazon's importance and complexity are not fully [...]