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Research conducted on mice has identified that the rapid response of a specific type of defense cell is essential for controlling Oropouche virus infections and preventing serious neurological damage. Without treatment, “Oropouche fever” causes symptoms including headaches, muscle and joint pain, skin rashes, and vomiting. In severe cases, it can lead to meningitis and encephalitis. Pregnant women are at risk of complications, including miscarriage. These findings will contribute to [...]

Despite their importance to water security and their legal protection, diffuse seeps – which are primarily responsible for the formation of wetlands in Brazil’s Cerrado savanna biome – continue to be systematically neglected by public policies, environmental consultants, rural landowners, and regulatory agencies. A group of Brazilian researchers points to the disconnect between technical and legal language as one of the main causes of this institutional [...]

According to research conducted by Brazilian scientists, high glucose levels may serve as a biomarker indicating a worse outcome in patients who have experienced their first acute myocardial infarction. The study demonstrated that glycemic variability, particularly glycemic delta, is associated with the size of the infarction and a reduction in left ventricular ejection fraction (LVEF). LVEF shows the strength of the heart’s contraction; if it is reduced, heart failure may [...]

 One of the largest Brazilian studies on colorectal cancer has revealed how genetic variations and genetic ancestry can influence the risk of developing the disease. The study, conducted by researchers at Hospital de Amor (formerly Hospital de Câncer de Barretos, in the interior of the state of São Paulo) and other institutions and funded by FAPESP, contributes to understanding the complex genetic reality of a highly mixed population such as Brazil’s. It [...]

Deforestation in the Brazilian Amazon is responsible for approximately 74.5% of the reduction in rainfall and 16.5% of the temperature increase in the biome during the dry season. For the first time, researchers have quantified the impact of vegetation loss and global climate change on the forest. A study led by scientists from the University of São Paulo (USP) in Brazil provides fundamental results to guide effective mitigation and adaptation strategies. These are the target themes [...]

A study conducted by researchers from the Pennington Biomedical Research Center (PBRC, United States), Proteimax Biotechnology (Israel), and the University of São Paulo’s Biomedical Sciences Institute (ICB-USP, Brazil) showed that ingesting Pep19 helps reduce visceral fat and improve sleep in obese adults. The molecule is a synthetic version of a peptide (a very small piece of protein) naturally found in human cells. Previous studies on animals have shown that Pep19 has anti-obesity [...]

A new species of bacteria of the genus Bartonella has been found in the Amazon National Park in the state of Pará, Brazil, in phlebotomine insects, also known as sand flies. This type of insect is generally associated with transmitting leishmaniasis, but according to the researchers, the DNA of the newly discovered microorganism is similar to that of two other Andean species of bacteria, B. bacilliformis and B. ancashensis. These bacteria cause Carrión’s disease (also known as Peruvian [...]

A set of bones belonging to sauropods, as long-necked dinosaurs are called, found in the municipality of Ibirá in the state of São Paulo, Brazil, reveals that the region was conducive to a bone disease that was fatal to these animals. Supported by FAPESP, the researchers found signs of osteomyelitis, a bone disease that can be caused by bacteria, viruses, fungi, or protozoa, in the fossils of six individuals from the Cretaceous period, approximately 80 million years ago. The bones show [...]

The COVID-19 virus hijacks the machinery of testicular cells that produce the hormone testosterone in order to replicate. It also appropriates the metabolic pathways of these cells and cholesterol, a precursor of testosterone, thereby altering lipid metabolism for its formation. This was verified in a study conducted in Brazil by researchers from the Araraquara School of Dentistry at São Paulo State University (FOAr-UNESP), in partnership with the Ribeirão Preto School of Medicine at the [...]