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Tricking fungi into thinking they're starving could be the key to slowing down our evolutionary arms race with fungal pathogens, as hungry fungi don't want to have sex. That's the conclusion from new research at the University of Bath which for the first time characterised a group of receptors unique to fungi, which prevent them from reproducing sexually. The research team, from the University of Bath and University of São Paulo - Ribeirão Preto, believe these [...]

Thanks to a new injectable formula, Brazilian researchers have succeeded in enhancing the efficacy and prolonging the duration of action of a drug commonly used to treat joint inflammation. The innovation involves lipid nanoparticles containing a high concentration of the active principle, which is gradually released into the affected joint to sustain the desired effect for up to ten days without the need for repeated administration of the drug. In an article published in the journal [...]

A study published in PLOS ONE shows that the larvae of the Brazilian stingless bee Scaptotrigona depilis depend on interactions between three different species of fungus to complete their development and reach adulthood. The complex process of symbiosis was studied by Brazilian and US researchers as part of a Thematic Project supported by São Paulo Research Foundation - FAPESP and the US National Institutes of Health (NIH). The study was conducted under the auspices of the FAPESP [...]

An article recently published in Science, entitled "The global tree restoration potential" , presents what it calls "the most effective solution at our disposal to mitigate climate change". The lead author is Jean-François Bastin, an ecologist affiliated with the Swiss Federal Institute of Technology (ETH Zurich). The article attracted enormous media attention. It reports the results of a study in which Bastin and collaborators used remote sensing and modeling [...]

Despite humanity's best efforts to eradicate malaria, the disease struck more than 200 million people in 2017, according to the World Health Organization. Worse yet, the parasite that causes malaria is developing resistance to many antimalarial drugs, including the mainstay, chloroquine. Researchers are actively searching for new treatments, and now, a group reporting in ACS Omega have found that aҫaí berry extracts can reduce parasites in the blood and prolong the [...]

Energy is information. Lengthening the time during which a system is capable of retaining energy before losing it to the local environment is a key goal for the development of quantum information. This interval is called the "coherence time". Several studies have been performed with the aim of retarding decoherence. A study conducted by researchers at the University of Campinas's Gleb Wataghin Institute of Physics (IFGW-UNICAMP) in São Paulo State, Brazil, in partnership [...]

An international group of researchers has proven that a molecule called TCMDC-135051 can selectively inhibit a protein that is essential to the lifecycle of Plasmodium falciparum, one of the parasites that causes malaria. The results of the study, just published in the journal Science, pave the way for the development of a new antimalarial drug. Malaria kills nearly 500,000 people per year, and more than 200 million new cases of the disease are reported annually. One of the obstacles to [...]

Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other conditions. The Nobel Prize in Physiology or Medicine in 1998 was awarded jointly to Robert F. Furchgott, Louis J. Ignarro and Ferid Murad for groundbreaking research of nitric oxide [...]

A new material with antifungal and antitumor properties has been developed by researchers at the Center for Development of Functional Materials (CDMF), one of the Research, Innovation and Dissemination Centers (RIDCs) supported by São Paulo Research Foundation – FAPESP. CDMF is hosted by the Federal University of São Carlos (UFSCar) in São Paulo State, Brazil. The compound was obtained from a sample of pure silver tungstate (a-Ag2WO4) irradiated with electrons and [...]