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In a groundbreaking advance in protein biophysics, researchers have unveiled detailed insights into the energy landscapes of proteins, challenging long-standing assumptions about protein stability and cooperativity. By harnessing site-resolved hydrogen-deuterium exchange (HDX) nuclear magnetic resonance (NMR) and innovative protein design strategies, the study reveals that low cooperativity in protein folding is typically associated with clusters of unstable residues rather than uniformly [...]

In a remarkable convergence of electrochemistry and sustainable synthesis, researchers from the Center for Development of Functional Materials (CDMF) at the Federal University of São Carlos (UFSCar) in Brazil have charted a new path toward the green production of amines. This breakthrough provides an alternative to traditional chemical routes by synthesizing key amine compounds directly from atmospheric nitrogen (N₂) via an innovative electrochemical process. Published in the journal ACS [...]

In a breakthrough that promises to transform agricultural monitoring and food safety, researchers at the São Carlos Institute of Physics of the University of São Paulo (IFSC-USP) in Brazil have unveiled a cutting-edge, biodegradable wearable sensor specifically designed for plants. This innovative device is capable of real-time, non-destructive detection of pesticides and other vital indicators of plant health, marking a significant leap in sustainable agricultural technology. Spearheaded by [...]

A groundbreaking study funded by the São Paulo Research Foundation (FAPESP) and published in the peer-reviewed journal Scientific Reports has unveiled a compelling link between fine particulate matter pollution in São Paulo, Brazil, and a heightened risk of kidney disease. This comprehensive research delves into the health ramifications of prolonged exposure to airborne particulate matter with a diameter smaller than 2.5 micrometers (PM2.5), a pollutant primarily generated from the combustion [...]

Advancing fertility preservation methods has immense significance, particularly for children and adolescents undergoing cancer treatments. A groundbreaking study led by Brazilian researchers at the University of São Paulo’s Medical School (FM-USP) presents a novel approach to enhance the success of autologous ovarian tissue transplantation. This method integrates melatonin delivery through an absorbable scaffold sponge, substantially improving graft viability—a crucial breakthrough in [...]

The São Paulo School of Advanced Science (SPSAS) on FoodOmics is set to take place from September 13 to 26, 2026, at the School of Food Engineering of the State University of Campinas (FEA-UNICAMP) in São Paulo, Brazil. This prestigious event will gather a diverse international community of researchers, students, and early-career scientists, focusing on the exciting and transformative field of FoodOmics. The interdisciplinary nature of FoodOmics integrates various omics technologies to [...]

In the realm of neurocritical care, time is the most precious commodity. The brain, an extraordinarily sensitive organ, can suffer irreversible damage within minutes when deprived of adequate oxygen. Unlike other tissues that withstand hypoxia over longer durations, the brain demands rapid and precise interventions to avoid lasting harm. However, clinical experience has repeatedly revealed the limitations of conventional monitoring methods in intensive care units (ICUs). Even when standard [...]

Brazil’s vast native biomes have long been recognized as critical reservoirs of biodiversity and essential components of the global carbon cycle. However, the conversion of these native ecosystems into agricultural landscapes has come at a substantial environmental cost. A recently published study in Nature Communications reveals that this land-use change has caused a staggering loss of approximately 1.4 billion tons of soil carbon, an amount that equates to the emission of 5.2 billion tons [...]

Emerging research from an international consortium of scientists at Monash University, the University of São Paulo, and Deakin University has unveiled alarming evidence linking the consumption of ultra-processed foods (UPFs) to deteriorations in cognitive function among middle-aged and older adults. Published in the highly respected journal Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, this cross-sectional study systematically investigates how heavily industrially [...]