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The blood test method makes use of machine learning and can be used to predict whether patients will put on weight, unless they change their habits. The project was conducted in Brazil with funding from FAPESP. Researchers at the University of Campinas (UNICAMP) in São Paulo State, Brazil, have developed a computer program that analyzes molecules in blood plasma to search for biomarkers that identify individuals who are at risk of becoming overweight and developing obesity-related [...]

Whether small-time farmers across the world get swept away by globalization or ride a wave of new opportunities depends largely on how much control they can get, according to a new study that takes a new, big-picture look. From soybean farmers in China to those who grow vanilla in Madagascar, trendy açaí in the Amazon or rubber in Myanmar, their place in new, fast-paced markets that can be both regional and global isn’t fully understood until examined in context with its [...]

Experiments with rats indicate that brain cells submitted to several forms of hypoxia underwent alterations to their energy production mechanism. Such condition may affect the fetus in pregnant women who have developed pre-eclampsia The lack of oxygen in the period antipating child birth – a condition that may affect children of pregnant women subjected to a high blood pressure disorder called pre-eclampsia – has been pointed as was one of the causes of schizophrenia. In an article [...]

In addition to helping us chew and swallow, keeping the mouth moist and protecting us against germs, saliva can also be used for early detection of the risk of developing diseases associated with surplus body fat. Researchers at the Federal University of São Paulo (UNIFESP) and the University of Campinas (UNICAMP) in Brazil performed a study in which they used the level of uric acid in saliva to predict body fat percentages in teenagers and identify those with surplus fat even if they [...]

Researchers Butantan Institute succeeded in reducing the toxicity and potentiating the analgesic effect of crotoxin by encapsulating it in nanostructured silica — the results of tests in an animal model of neuropathic pain are promising Crotoxin, extracted from the venom of the South American rattlesnake Crotalus durissus terrificus, has been studied for almost a century for its analgesic, anti-inflammatory and antitumor activities and as an even more powerful muscle paralyzer than [...]

In an article published in the journal PLOS ONE, a group of researchers supported by FAPESP has updated the description of the Ghost knifefish Tembeassu marauna, a Neotropical electric fish species found only once in the wild. The study, conducted in Brazil, was based on an analysis of external anatomy and, above all, on internal details that could be seen thanks to an advanced, high-resolution computed tomography (CT) technique that revealed characteristics of the fish’s bones without [...]

WEST LAFAYETTE, Ind. – The global gene therapy market is expected to reach $13 billion by 2024 as new treatment options target cancers and other diseases. Now, a team of scientists from Purdue University and other research institutions around the world have come together to better understand the growing number of worldwide patented innovations available for gene therapy treatment. They specifically focus on nonviral methods, which use synthetic or natural compounds or physical forces to [...]

Compounds based on palladium, a metal belonging to the same group as platinum, have been developed by researchers from Brazil, the UK and Italy — In vitro tests show action against tumor cells that are resistant to treatment currently used A group led by a researcher affiliated with the University of São Paulo’s São Carlos Chemistry Institute (IQSC-USP) in Brazil has developed a novel palladium compound that acts against ovarian tumor cells without affecting healthy [...]

A Brazilian study published in the journal Drug and Alcohol Dependence shows that cannabis smoked recreationally does not work as a harm reduction strategy for crack and cocaine addicts undergoing rehabilitation. Instead of reducing their craving for cocaine, whether nasally insufflated in powder form or smoked in the form of crack crystals, cannabis use made the patients’ clinical condition worse. The patients were evaluated for six months after discharge from a voluntary inpatient [...]