As per a workforce of researchers in Brazil, the SARS-CoV-2 virus can’t solely infect tissues which produce salivary glands in our physique but additionally flip them into reservoirs where it replicates. As per the researchers, this may very well be magnifying its infectious potential.
The examine’s findings had been first revealed in an article within the Journal of Pathology. It helps perceive why the COVID-19 virus is discovered abundantly in saliva, which resulted within the improvement of saliva-based diagnostic testing strategies just like the RT-PCR check.
As per Bruno Fernandes Matuck, doctoral candidate at USP’s Dental School, “This is the first report of a respiratory virus’s capacity to infect and replicate in salivary glands. Until now it was thought that only viruses that cause highly prevalent diseases such as herpes used salivary glands as reservoirs. The discovery may help explain why SARS-CoV-2 is so infectious,”
The elevated infectiousness of COVID-19 virus compares to other respiratory viruses spurred the speculation that it could be current in saliva with out coming into contact with nasal and lung secretions, replicating in salivary gland cells.
The examine noticed tissue samples from 24 sufferers who succumbed to Covid-19. It discovered that two-thirds of the samples not simply confirmed presence of the virus but additionally its replication in cells.
“We observed several viruses clustering in salivary gland cells, which showed that they were replicating there. They weren’t in these cells passively,” Bruno Fernandes Matuck stated.