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A study reported in Proceedings of the National Academy of Sciences (PNAS) shows how the presence of a specific protein called IL-22BP affects the composition of the gut microbiota and the body's response to bacterial infection. We discovered that mice that don't produce this protein are more protected against intestinal infections by bacteria like Clostridioides difficile and Citrobacter rodentium. ” Marco Aurélio Ramirez Vinolo, co-author of the article He is a [...]

The chikungunya virus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes and responsible for more than 900 deaths in Brazil since it arrived around ten years ago, is capable of spreading through the blood, reaching multiple organs and crossing the blood-brain barrier, which protects the central nervous system. The mechanisms of action observed for the first time in fatal cases by a group of Brazilian, American and British researchers were reported in an [...]

One 30-minute session of moderate walking can lower the systolic blood pressure of women with rheumatoid arthritis, according to a new study. Many people with rheumatoid arthritis also experience high blood pressure, which can lead to cardiovascular issues. The authors of the study believe the effect of these exercise sessions can result in a permanent lowering of systolic blood pressure. The study observed no similar reduction in diastolic blood pressure. Thirty minutes of moderate [...]

A novel peptide called Bc-7a from the venom of snakes – pit viper Cotiara and South American bushmaster was found to lower blood pressure by inhibiting the activity of angiotensin-converting enzyme, reveals a study published in Biochimie (1 Trusted Source A novel metalloproteinase-derived cryptide from Bothrops cotiara venom inhibits angiotensin-converting enzyme activity Go to source Novel Peptide from Snake Venom Can Reduce Blood Pressure Brazilian snake and [...]

Atopic dermatitis (AD) is a chronic inflammatory skin disease whose main symptoms are redness, swelling, and itchy rashes. It is more common in people with a genetic predisposition. Manifestation of symptoms depends on interactions among the immune system, environmental factors and gut microbiota. Many pieces of this complex jigsaw puzzle are still undiscovered, but recent research has identified relevant factors. For example, alterations in gut microbiota composition can contribute to the [...]

A study has indicated that the hormone, which is readily available for purchase from drugstores and frequently used as a supplement, intensified the symptoms of Crohn's disease and ulcerative colitis in laboratory mice. The effect, however, depended on the animal's gut microbiota profile. A new study recently published in the journal Microorganisms shows that melatonin, despite its antioxidant properties and role in sleep cycle regulation, could intensify intestinal inflammation and [...]

Experiments involving mice showed four weeks of training with weights to be sufficient to reverse behavioral and physical alterations characteristic of the disease. Regular physical exercise, such as resistance training, can prevent Alzheimer's disease, or at least delay the appearance of symptoms, and serves as a simple and affordable therapy for Alzheimer's patients. This is the conclusion of an article published in the journal Frontiers in Neuroscience by Brazilian researchers [...]

by José Tadeu Arantes, FAPESP Women's artistic gymnastics has attracted considerable attention at recent editions of the Olympic Games, thrilling huge crowds of spectators at the venue itself and gripping billions of viewers on TVs around the world. Murky and even unethical behavior may lie hidden behind these displays of beauty, grace and skill, however. Many countries subject their gymnasts to training regimes that involve sacrifices not seen by the fans or the media. In the [...]

A study conducted in Brazil and reported in an article published in Molecular Psychiatry suggests that schizophrenia may be associated with alterations in the vascularization of certain brain regions. Researchers at the State University of Campinas (UNICAMP), D’Or Research and Education Institute (IDOR) and the Federal University of Rio de Janeiro (UFRJ) found a link between astrocytes (central nervous system cells) from patients with schizophrenia and formation of [...]