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A study conducted at the University of São Paulo (USP) in Brazil and described in an article published in the journal Scientific Reports shows that anti-inflammatory drugs commonly taken by children may be associated with dental enamel defects (DEDs) currently seen in about 20% of children worldwide. The authors, who are affiliated with the Ribeirão Preto Dental School (FORP-USP) and School of Pharmaceutical Sciences (FCFRP-USP), investigated the effects of celecoxib and [...]

If you look at a net full of pacus (Piaractus mesopotamicus), you cannot distinguish with the naked eye which individuals will have descendants with higher filet yield or faster weight gain. Their growth can be monitored with a tape measure, and they can be weighed on a scale. The data can be tabulated and compared. But to breed an entire population with the right characteristics, some 2,000 fish per generation must be measured and weighed, and the task can take days. In [...]

A survey of 1,183 physicians in the Brazilian states of São Paulo and Maranhão shows that the various uses of telemedicine, which turned out to be a significant alternative during the public health crisis caused by COVID-19, are set to be a permanent feature of the nation’s health system. The study was conducted by researchers at the University of São Paulo (USP), the Federal University of Maranhão (UFMA) and Queen Mary University of London in the [...]

Vitamin D plays an important role in the regulation of calcium and phosphorus absorption by an organism. It also helps keep the brain and immune system working. Researchers at the Federal University of São Carlos (UFSCar) in Brazil and University College London (UCL) in the United Kingdom have now shown that vitamin D supplementation reduces the risk of dynapenia in older people by 78%. Dynapenia is an age-associated loss of muscle strength. It can be partially explained by muscle [...]

Depression affects 10%-16% of pregnant women worldwide. Most get better with the help of antidepressant drugs. Although the safety of using antidepressants during pregnancy is endorsed by science, their effects on fetal neurodevelopment are poorly understood and should be studied with advanced techniques such as genomics. This is the main conclusion reached by a group of Brazilian researchers in a review of more than 100 scientific articles on fetal exposure to these drugs, especially [...]

André Julião | Agência FAPESP – In Brazil, a group of researchers has reported the largest outbreak to date of COVID-associated candidemia caused by the same drug-resistant strain of Candida parapsilosis, a fungus that invades the bloodstream and can lead to death. The outbreak occurred in 2020-21 in an intensive care unit (ICU) at a tertiary referral hospital in Salvador, Bahia state, during one of the peaks of the COVID-19 pandemic. In an [...]

By Karina Toledo | Agência FAPESP – A study conducted in Brazil and reported in an article in Vaccines shows that in the São José do Rio Preto region in the northwest of São Paulo state, only 75.8% of children aged 0-15 have antibodies against measles. The proportion considered ideal to prevent outbreaks of the disease is 94%. The findings are in line with other recent surveys showing a drop in child vaccination rates in Brazil since 2015. “This is yet [...]

Researchers at the University of São Paulo (USP) in Brazil have found that severe COVID-19 is associated with an imbalance in an important immune system signaling pathway. The discovery helps explain at the molecular level why some people infected by SARS-CoV-2 develop a potentially fatal systemic inflammation. It also paves the way to the development of more specific therapies. The study is published in Frontiers in Immunology. The researchers detected dysregulation of [...]

Scientists affiliated with the Department of Physical Education’s Human Movement Laboratory (Movi-Lab) at São Paulo State University (UNESP) in Bauru, Brazil, are using artificial intelligence to help diagnose Parkinson’s disease and estimate its progression. An article published in the journal Gait & Posture reports the findings of a study in which machine learning algorithms identified cases of the disease by analyzing spatial and temporal gait parameters. The [...]