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AGÊNCIA FAPESP Estudo publicado na revista Science Advances descreveu, pela primeira vez, um circuito neuromuscular que liga a queima de gordura no músculo à ação de uma proteína no cérebro. Os resultados, obtidos por pesquisadores da Universidade Estadual de Campinas (Unicamp) e da Universidade de São Paulo (USP), ajudam a entender como a prática de exercício físico ajuda na perda de peso e reforçam a [...]

Spin is the intrinsic magnetic moment of a particle—an electron, for example. It is a fundamental magnitude, like mass and charge. Simply put, it is as if the particle had a magnet inside it that enabled it to interact, even while at rest, not only with the spins of other particles but also with external magnetic fields. By analogy with usual liquids, a system in which spins do not exhibit magnetic order, even at temperatures close to absolute zero, is termed a spin liquid. In [...]

The Laboratory of the Drug Discovery Division of the Institute of Biomedical Sciences of the University of São Paulo (ICB-USP), in partnership with researchers from the University of Hamburg and the German Electron Synchrotron (DESY) from Germany, has identified three possible compounds for the treatment of Covid-19. These are naturally occurring compounds selected from a screening of 500 drugs that have shown promising inhibition of the PLpro protein, one of the enzymes responsible [...]

A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system. A preliminary version (not yet peer-reviewed) posted in 2020 was one of the first to show that the virus that causes COVID-19 can infect brain cells, especially astrocytes. It also broke new ground by describing alterations in the structure of the cortex, the most neuron-rich brain region, even in cases of mild COVID-19. The cerebral cortex is the [...]

Newswise — A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system. A preliminary version (not yet peer-reviewed) posted in 2020 was one of the first to show that the virus that causes COVID-19 can infect brain cells, especially astrocytes. It also broke new ground by describing alterations in the structure of the cortex, the most neuron-rich brain region, even in cases of mild COVID-19. The cerebral [...]

According to a study, the amino acid taurine can be used in anti-aging therapy. Our cells produce potentially toxic by-products known as “free radicals” when they break down the oxygen we breathe and the food we consume every day in order to exist. Some of these molecules serve important biological functions, but if there are too many of them, internal cellular structures can be damaged, impairing the cells’ ability to function and possibly leading to chronic disease. We [...]

A fully national COVID-19 booster vaccine is ready for human trials. The innovative substance, developed by the Center for Vaccine Technology of the Federal University of Minas Gerais (CTVacinas-UFMG) in partnership with Fundao Oswaldo Cruz (Fiocruz), targets a different viral protein than other immunizers targeting Sars-CoV-2. . In an article published in the journal Nature Communications, the authors of the study reported that the so-called SpiN-Tec elicited a strong immune system response to [...]

A study by scientists from Brazil, Australia, Austria and the United States has made important discoveries about a type of childhood cancer that has no approved cure and has a low survival rate. Findings described in an article published in the journal Neurooncology pave the way for finding more specific treatments. “Ependymomas are tumors of the central nervous system of various types, which are mainly treatable only by surgical removal and radiation therapy. Our study focused on gene [...]

Uma nova vacina contra a covid-19 desenvolvida no Brasil pode começar a ser testada em humanos ainda neste ano. O imunizante apresentou bons resultados nos estudos com animais, que foram divulgados este mês na revista Nature Communications. Os cientistas já receberam autorização da Comissão Nacional de Ética em Pesquisa (Conep) para dar início ao ensaio clínico e aguardam, agora, o sinal verde da Agência Nacional de [...]