Veículo
Scicasts (Reino Unido)
Em 2024: 0 notícias
Desde 1995: 6 notícias
Study Explains Epigenetic Mechanisms Behind Autoimmune Diseases
Publicado em 04 agosto 2018
São Paulo, Brazil (Scicasts) — A group of researchers at the University of São Paulo (USP) in Brazil used a DNA editing tool called CRISPR/Cas9 to manipulate on of the genes associated to the autoaggressive T lymphocytes responsible for inducing autoimune diseases such as autoimmune polyglandular syndrome type 1 (APS-1) and type 1 diabetes.
The autoimmune regulator or "Aire" gene acting in medullary thymic epithelial cells (mTECs) was recently described as playing an important role in [...]
-
Study Shows How Oropouche Virus Replicates in Human Cells
Publicado em 31 julho 2018São Paulo, Brazil (Scicasts) — The strategy used by the Oropouche virus to replicate in human cells has been described for the first time by researchers at the University of São Paulo (USP) in Brazil and international collaborators in an article published in the journal PLOS Pathogens. According to the study, shortly after invading the cell, the pathogen "hijacks" an organelle called the Golgi complex, which becomes a veritable virus factory. The virus does this by recruiting host cell [...]ver notícia -
Identified RNA Molecules that Regulate Action of Male Hormone in Prostate Cancer
Publicado em 19 julho 2018São Paulo, SP, Brazil (Scicasts) — A study detected in tumoural tissue hundreds of RNAs that do not encode proteins but appear to regulate effects of androgens and androgen receptors on gene expression in tumours. In most cases of prostate cancer, tumour cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone (DHT). For this to happen, these hormones have to bind to androgen receptors, proteins located mostly in the cytoplasm of [...]ver notícia -
Platform Uses Artificial Intelligence to Diagnose Zika and Other Pathogens
Publicado em 12 junho 2018São Paulo, Brazil (Scicasts) — A platform that can diagnose several diseases with a high degree of precision using metabolic markers found in patients' blood has been developed by scientists at the University of Campinas (UNICAMP) in Brazil. The method combines mass spectrometry, which can identify tens of thousands of molecules present in blood serum, with an artificial intelligence algorithm capable of finding patterns associated with diseases of viral, bacterial, fungal and even genetic [...]ver notícia -
Current Deforestation Pace will Intensify Global Warming, Study Alerts
Publicado emSão Paulo, Brazil (Scicasts) — The global warming process may be even more intense than originally forecast unless deforestation can be halted, especially in the tropical regions. "If we go on destroying forests at the current pace - some 7,000 km² per year in the case of Amazonia - in three to four decades, we'll have a massive accumulated loss. This will intensify global warming regardless of all efforts to reduce greenhouse gas emissions," says Paulo Artaxo, a professor at the [...]ver notícia -
Study of Nervous System Cells Can Help to Understand Degenerative Diseases
Publicado em 17 agosto 2017São Paulo, Brazil (Scicasts) — The results of a new research showed that many of the genes that are expressed by microglia are different between humans and mice, which are frequently used as animal models in research on Alzheimer's disease and other neurodegenerative disorders. Microglia are the primary immune cells of the central nervous system, with functions similar to those of white blood cells, especially in actively defending the brain and spinal cord. The collaborative research by [...]ver notícia