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The onset of any bodily train program causes muscle ache that may hinder actions so simple as getting up from a settee. With time and a bit of persistence, the muscular tissues grow to be accustomed to the hassle, creating extra power and endurance. Researchers affiliated with Harvard College in the US and the College of São Paulo (USP) in Brazil describe the mobile mediator that makes this adaptation to train doable within the journal Cell. The mediator is succinate, a metabolite [...]