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A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to a Brazilian study reported in the Journal of Medical Virology. The study confirmed the vaccine’s effectiveness and its importance to control of the disease, while also showing that, more than three years after the first application of a COVID-19 vaccine in Brazil, the [...]

The concept of “One Health” – which emphasizes the relationship between human, animal, plant and environmental health – has been gaining ground in scientific discussions in recent years. Brazilian and North American researchers developing research using this approach presented their work on Tuesday (April 9th), in Chicago (United States), during FAPESP Week Illinois. One of the panelists was Eduardo Esteban Bustamante, a professor at the University of Illinois in [...]

Weight training can help reduce body fat and increase muscle strength and mass in older people, contributing to functional autonomy and avoidance of falls and injury. Furthermore, recent studies have shown that it can also benefit the mental health of older people, especially those who suffer from anxiety and depression. These benefits were confirmed by a study reported in the journal Psychiatry Research. The study involved a systematic review and meta-analysis of more than 200 articles on [...]

The chikungunya virus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes and responsible for more than 900 deaths in Brazil since it arrived around ten years ago, is capable of spreading through the blood, reaching multiple organs and crossing the blood-brain barrier, which protects the central nervous system. The mechanisms of action observed for the first time in fatal cases by a group of Brazilian, American and British researchers are reported in an article published in Cell [...]

FAPESP Older people with frailty syndrome should be prioritized in primary health care because they are more likely to suffer from falls, hospitalizations, incapacitation, and early death. The syndrome is characterized by the presence of three or more of the following factors: involuntary weight loss, fatigue, muscle weakness, slow gait, and a low level of physical activity. A study conducted by researchers at the Federal University of São Carlos (UFSCar) in Brazil and University [...]

Offspring of rats that consume excessive amounts of fructose develop disturbances in the autonomic nervous, cardiovascular, and metabolic systems at an early age, increasing the risk of chronic diseases such as diabetes and obesity in adulthood, according to a study conducted by Brazilian scientists. The study is published in the International Journal of Obesity. The findings confirm information in the scientific literature regarding the appearance of metabolic disorders such as high levels [...]

Introduction Tuberculosis (TB) is a highly infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body. According to the World Health Organization (WHO), TB is one of the top 10 causes of death worldwide, with an estimated 10 million people falling ill with the disease in 2019 alone. The Study A recent study conducted by University of São Paulo has shed light on a mechanism that aggravates [...]

Blood clotting (thrombosis) in the capillary vessels of the lungs is one of the first consequences of severe COVID-19, even preceding the respiratory distress caused by diffuse alveolar damage, according to a Brazilian study reported in an article published in the Journal of Applied Physiology. Autopsies of nine patients who died after developing the severe form of the disease showed a clearly typified condition involving alterations to lung vascularization and thrombosis. For the first [...]

A study conducted at the University of São Paulo helps explain why older people are more susceptible to the severe form of the disease and why it involves blood clotting disorders. A study conducted at the University of São Paulo helps explain why older people are more susceptible to the severe form of the disease and why it involves blood clotting disorders. – An article published in NPJ Aging, a Springer Nature journal, reveals that natural production of [...]