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Postdoctoral Fellow – microRNAs and GLUT4 expression in diabetes Universidade de São Paulo

Publicado em 15 agosto 2017

Date Posted

Aug. 15, 2017

Job Title

Postdoctoral Fellow – microRNAs and GLUT4 expression in diabetes

Department

Institute of Biomedical Sciences

Department Website

http://www.fisio.icb.usp.br:488

Institution

Universidade de São Paulo

São Paulo, São Paulo

Brazil

Application Deadline

Sep. 10, 2017

Position Start Date

October/November 2017

Website For Job

http://www.fapesp.br/oportunidades

Job Categories

Post-Doc

Academic Fields

Biology - Molecular

Postdoctoral Fellow – The role of microRNAs in the regulation of GLUT4 expression in diabetes mellitus

The Laboratory of Endocrinology and Metabolism, Institute of Biomedical Sciences, University of São Paulo, Brazil, is offering post-doctorate training in the epigenetic regulation of glucose transporters, with FAPESP (São Paulo Research Foundation) financial support. Application deadline is September 10, 2017.

The scholarship is linked to the Thematic Project "Unraveling mechanisms of glycemic control and chronic complications of diabetes mellitus: contributions to human health", supported by FAPESP (#2016/15603-0), and coordinated by Dr. Ubiratan Fabres Machado. The general objective is to uncover molecular mechanisms related to glycemic control and the development of complications in patients with T1DM and/or T2DM, and includes the epigenetic regulation of glucose transporters in different tissues. Candidates must hold PhD Degree in Health Sciences, related to metabolism of carbohydrates and diabetes mellitus. The present Post-Doctorate project aims to investigate the epigenetic regulation, mediated by microRNAs, of the GLUT4 protein expression (codified by the Slc2a4 gene) in skeletal muscle of T2DM mice. Candidates must have proven experience and knowledge in evaluation and validation of microRNAs, analysis of Slc2a4/GLUT4 expression and of activity of related transcriptional factors, and evaluation of muscle metabolism in diabetes mellitus. Besides, it is also necessary to have experience in: qPCR for mRNAs and miRNAs, Western blotting, EMSA, ChIP assay, in silico analysis of miRNAs, experimental models of T1DM and T2DM. skeletal muscle electrical stimulation and incubation in vitro, and data analysis tools. Applicants must send (1) presentation letter summarizing the reason of interest in the scholarship and previous scientific experience, (2) two letters of references, and (3) a short CV (foreign applicants) or "Currículo Lattes" (Brazilians), to Dr. Ubiratan Fabres Machado: ubiratan@icb.usp.br.

EEO/AA Policy

All qualified applicants will receive consideration for the position without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, or disabled status. We seek candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence.

Please reference AcademicKeys.com in your cover letter when applying for or inquiring about this job announcement.

Contact Information

Contact

Ubiratan Fabres Machado

Institute of Biomedical Sciences

Universidade De São Paulo

São Paulo, São Paulo

Brazil

Email:

ubiratan@icb.usp.br