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Researchers at the Center for Research on Redox Processes in Biomedicine (Redoxome) in Brazil have identified extracellular matrix proteins modified by the action of hypobromous acid in normal and fibrotic lung tissues, suggesting a possible physiological role for protein bromination.
This is the first study to identify brominated proteins in pulmonary fibrosis and non-fibrotic lung tissue.
Redoxome is a Research, Innovation and Dissemination Center (RIDC) funded by FAPESP and hosted by [...]
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Fenômeno conhecido como bromação de proteínas foi observado por cientistas do Centro de Processos Redox em Biomedicina em tecidos pulmonares normais e fibróticos
A matriz extracelular é uma rede intrincada composta por um conjunto de macromoléculas que une e fixa as células para formar os tecidos, desempenhando funções vitais de suporte celular, comunicação intercelular e regulação do [...]
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A matriz extracelular é uma rede intrincada composta por um conjunto de macromoléculas que une e fixa as células para formar os tecidos, desempenhando funções vitais de suporte celular, comunicação intercelular e regulação do desenvolvimento tecidual. Em estudo publicado na revista Redox Biology, pesquisadores identificaram proteínas da matriz extracelular modificadas pela ação do ácido hipobromoso [...]
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A matriz extracelular é uma rede intrincada composta por um conjunto de macromoléculas que une e fixa as células para formar os tecidos, desempenhando funções vitais de suporte celular, comunicação intercelular e regulação do desenvolvimento tecidual. Pesquisadores identificaram proteínas da matriz extracelular modificadas pela ação do ácido hipobromoso em tecidos pulmonares com fibrose e em tecidos [...]
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Researchers at the Center for Research on Redox Processes in Biomedicine (Redoxome) in Brazil have identified extracellular matrix proteins modified by the action of hypobromous acid in normal and fibrotic lung tissues, suggesting a possible physiological role for protein bromination. This is the first study to identify brominated proteins in pulmonary fibrosis and non-fibrotic lung tissue.
The extracellular matrix is a complex three-dimensional network of proteins and other macromolecules [...]
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Researchers at the Center for Research on Redox Processes in Biomedicine (Redoxome) in Brazil have identified extracellular matrix proteins modified by the action of hypobromous acid in normal and fibrotic lung tissues, suggesting a possible physiological role for protein bromination. This is the first study to identify brominated proteins in pulmonary fibrosis and non-fibrotic lung tissue.
The extracellular matrix is a complex three-dimensional network of proteins and other macromolecules [...]
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Researchers at the Center for Research on Redox Processes in Biomedicine (Redoxome) in Brazil have identified extracellular matrix proteins modified by the action of hypobromous acid in normal and fibrotic lung tissues, suggesting a possible physiological role for protein bromination. This is the first study to identify brominated proteins in pulmonary fibrosis and non-fibrotic lung tissue. Researchers at the Center for Research on Redox Processes in Biomedicine (Redoxome) in Brazil have [...]
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by FAPESP
Researchers at the Center for Research on Redox Processes in Biomedicine (Redoxome) in Brazil have identified extracellular matrix proteins modified by the action of hypobromous acid in normal and fibrotic lung tissues, suggesting a possible physiological role for protein bromination. This is [...]
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Proteins Modified in Lungs: Clues to Bromine's Biological Functions
Bromine is a halogen element that plays a crucial role in various biological processes. Recent research has uncovered the significance of proteins modified in the lungs by bromine, shedding light on its biological functions and potential implications for human health.
Studies have shown that bromine can modify proteins in the lungs, leading to alterations in their structure and function. These modifications [...]
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Cientistas do Centro de Pesquisa em Processos Redox em Biomedicina (Redoxoma), um Centro de Pesquisa, Inovação e Difusão (CEPID) financiado pela FAPESP e sediado no Instituto de Química (IQ) da Universidade de São Paulo (USP), propõem um mecanismo para explicar como o ácido úrico causa lesões vasculares que podem levar a doenças cardiovasculares.
O ácido úrico, um metabólito abundante no [...]
