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Los linfocitos T CD4+ son células importantes para la respuesta inmunológica durante las infecciones pulmonares, pero cuando surgen en exceso pueden causar daños a estos órganos. Mediante experimentos con ratones, investigadores de la Universidad de Sao Paulo, en Brasil, descubrieron la causa de esta respuesta exagerada.
Los linfocitos T CD4+ han sido ampliamente descritos en la literatura científica por su importante rol en la respuesta inmunológica [...]
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Los linfocitos T CD4+ han sido ampliamente descritos en la literatura científica por su importante rol en la respuesta inmunológica durante las infecciones pulmonares. Pero una investigación publicada en la revista Cell Reports ha demostrado ahora que una acumulación excesiva de estas células de defensa en los tejidos pulmonares –responsables de los intercambios gaseosos esenciales para la respiración– aparece asociada a daños en los [...]
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CD4 + T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections. However, an article published in the journal Cell Reports shows that an imbalance in the volumes of these defense cells in different parts of the lung in response to infection can do more harm than good.
The study described in the article involved infecting mice with hypervirulent tuberculosis and influenza. The authors concluded that an “ideal [...]
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São Paulo, Brazil – CD4 + T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections. However, an article published in the journal Cell Reports shows that an imbalance in the volumes of these defense cells in different parts of the lung in response to infection can do more harm than good.
The study described in the article involved infecting mice with hypervirulent tuberculosis and influenza. The authors [...]
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CD4 + T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections. However, an article published in the journal Cell Reports shows that an imbalance in the volumes of these defense cells in different parts of the lung in response to infection can do more harm than good.
The study described in the article involved infecting mice with hypervirulent tuberculosis and influenza. The authors concluded that an "ideal [...]
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Yixue
- Publicado em 09 de fevereiro de 2024
CD4 + T 细胞因其在肺部感染免疫反应中发挥的重要作用而在科学文献中得到强调。然而, 《细胞报告》 杂志上发表的一篇文章 表明,肺部不同部位的这些防御细胞在应对感染时数量不平衡可能弊大于利。
文章中描述的研究涉及用高毒力结核病和流感感染小鼠。作者得出的结论是, 肺部需要“理想量”的 CD4 + T [...]
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T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections. However, an article published in the journal Cell Reports shows that an imbalance in the volumes of these defense cells in different parts of the lung in response to infection can do more harm than good.
The study described in the article involved infecting mice with hypervirulent tuberculosis and influenza. The authors concluded that an [...]
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CD4+ T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections. However, an article published in the journal Cell Reports shows that an imbalance in the volumes of these defense cells in different parts of the lung in response to infection can do more harm than good.
The study described in the article involved infecting mice with hypervirulent tuberculosis and influenza. The authors concluded [...]
-
CD4+ T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections. However, an article published in the journal Cell Reports shows that an imbalance in the volumes of these defense cells in different parts of the lung in response to infection can do more harm than good.
The study described in the article involved infecting mice with hypervirulent tuberculosis and influenza. The authors [...]
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Introduction
Tuberculosis (TB) is a highly infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body. According to the World Health Organization (WHO), TB is one of the top 10 causes of death worldwide, with an estimated 10 million people falling ill with the disease in 2019 alone.
The Study
A recent study conducted by University of São Paulo has shed light on a mechanism that aggravates [...]