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Este fenómeno, que se encuadra en la llamada epigenética, puede estar asociado a patologías como el alzhéimer. El referido trabajo, realizado en la Universidad de São Paulo, en Brasil, expande el conocimiento sobre el sistema nervioso central.
La proteína PKMzeta está reconocidamente vinculada a los procesos de formación de la memoria: el alzhéimer, la depresión y el propio envejecimiento están asociados a [...]
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研究人员使用表观遗传学来研究调节记忆基因活性的机制，这可能与阿尔茨海默病等疾病有关。这一发现扩展了科学家对中枢神经系统的认识。
圣保罗研究基金会
4月18日消息
已知 PKMzeta [...]
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A new study discovers the mechanism that explains the association between decreased levels of PKMzeta protein and Alzheimer's disease. The findings are published in the journal Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms.//
To understand the mechanism, the researchers used epigenetics, the science of how environmental stimuli activate or inhibit gene expression without altering the DNA sequence. An epigenetic technique often used by researchers is [...]
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The protein PKMzeta has been strongly associated with long-term memory formation. Decreased levels of this protein in the brain are associated with neurological illnesses such as Alzheimer’s disease, depression, and aging.
Working at the University of São Paulo in Brazil, the researchers used epigenetics to study the mechanism, which could be associated with pathologies such as Alzheimer’s. The discovery expands scientists’ knowledge of the central nervous system. [...]
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Summary: DNA methylation regulates the expression of PKMzeta, a gene involved in the formation of long-term memory. Decreased levels of PKMzeta in the brain are associated with Alzheimer’s disease and other memory disorders.
Source: FAPESP
It is known that the protein PKMzeta is associated with the formation of long-term memory. Neurological diseases such as Alzheimer’s disease, as well as depression and aging, are correlated with decreased levels of this protein in the [...]
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Summary: DNA methylation regulates the expression of PKMzeta, a gene involved in the formation of long-term memory. Decreased levels of PKMzeta in the brain are associated with Alzheimer’s disease and other memory disorders.
Source: FAPESP
It is known that the protein PKMzeta is associated with the formation of long-term memory. Neurological diseases such as Alzheimer’s disease, as well as depression and aging, are correlated with decreased levels of this protein in the [...]
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The protein PKMzeta is known to be associated with long-term memory formation. Neurological disorders such Alzheimer’s disease, as well as depression and aging, correlate with reduced levels of this protein in the brain. Researchers affiliated with institutions in Brazil and the United States have now discovered a mechanism that helps explain the link and could pave the way to future medical innovations. Their study is reported in article published in the journal Biochimica [...]
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Summary: DNA methylation regulates the expression of PKMzeta, a gene implicated in long-term memory formation. Reduced levels of PKMzeta in the brain are associated with Alzheimer’s disease and other memory loss disorders.
Source: FAPESP
PKMzeta protein is known to be associated with long-term memory formation. Neurological disorders such as Alzheimer’s disease, as well as depression and aging, are associated with decreased levels of this protein in the brain.
Researchers [...]
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Summary: DNA methylation regulates the expression of PKMzeta, a gene implicated in long-term memory formation. Reduced levels of PKMzeta in the brain are associated with Alzheimer’s disease and other memory deficit disorders.
Source: FAPESP
The protein PKMzeta is known to be associated with long-term memory formation. Neurological disorders such Alzheimer’s disease, as well as depression and aging, correlate with reduced levels of this protein in the brain.
Researchers [...]
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by Theo Ruprecht, FAPESP
The protein PKMzeta is known to be associated with long-term memory formation. Neurological disorders such Alzheimer's disease, as well as depression and aging, correlate with reduced levels of this protein in the brain. Researchers affiliated with institutions in Brazil and the United States have now discovered a mechanism that helps explain the link and could pave the way to future medical innovations. Their study is reported in article published in the journal [...]
