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021年1月5日 讯 /生物谷BIOON/ [...]
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Researchers affiliated with the University of Sao Paulo in Brazil have used epigenetic modulators to reduce stress-induced damage to neuroplasticity, and thus resolve symptoms of depression in rats. Whereas conventional antidepressants need to be taken repeatedly before they take effect, their current interventions worked after one dosage.
Stress is known to alter certain epigenetic markers associated with neuroplasticity in the brain. In particular, it increases DNA methylation, a [...]
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By Karina Ninni | Agência FAPESP – Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time – around three to five weeks – to have the desired effect. A group of researchers affiliated with the University of São Paulo (USP) in Brazil set out to tackle the second problem by using epigenetic modulators to try to [...]
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By Karina Ninni | Agência FAPESP – Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time – around three to five weeks – to have the desired effect. A group of researchers affiliated with the University of São Paulo (USP) in Brazil set out to tackle the second problem by using epigenetic modulators to try to [...]
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By Karina Ninni | Agência FAPESP – Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time – around three to five weeks – to have the desired effect. A group of researchers affiliated with the University of São Paulo (USP) in Brazil set out to tackle the second problem by using epigenetic modulators to try to [...]
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Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time – around three to five weeks – to have the desired effect. A group of researchers affiliated with the University of São Paulo (USP) in Brazil set out to tackle the second problem by using epigenetic modulators to try to “erase” the consequences of [...]
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Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time – around three to five weeks – to have the desired effect. A group of researchers affiliated with the University of São Paulo (USP) in Brazil set out to tackle the second problem by using epigenetic modulators to try to “erase” the consequences of stress. [...]
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The research group used epigenetic modulators to try to ‘erase’ the damage done by stress to neuroplasticity. The study showed that acute intervention in epigenetic mechanisms produces antidepressant-like effects more rapidly than conventional drugs
Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time – around three to [...]
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Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time – around three to five weeks – to have the desired effect. A group of researchers affiliated with the University of São Paulo (USP) in Brazil set out to tackle the second problem by using epigenetic modulators to try to “erase” the consequences of stress. [...]
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The research group used epigenetic modulators to try to ‘erase’ the damage done by stress to neuroplasticity. The study showed that acute intervention in epigenetic mechanisms produces antidepressant-like effects more rapidly than conventional drugs
Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time – around three to [...]
