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Glutamatergic Medications Show Promise for Obsessive-Compulsive Disorders

Publicado em 03 janeiro 2025
Glutamatergic medications showed promise in treating obsessive-compulsive and related disorders (OCRDs), especially obsessive-compulsive disorder (OCD), a systematic review and meta-analysis showed. Across 27 trials, glutamatergic medications as monotherapy or added to selective serotonin reuptake inhibitors (SSRIs) showed a large effect size in improving OCRD symptoms (Cohen d -0.80, 95% CI -1.13 to -0.47) when the intervention group was compared with the control group, with low certainty [...]