Notícia

Moneyrf.com

One-third of younger age groups in northwestern São Paulo lack antibodies against measles

Publicado em 16 abril 2020

In São José do Rio Preto, state of São Paulo (Brazil), almost a third of the population aged 10-40 are estimated to have no antibodies against measles, according to a new study that tested 981 people in various age groups. São José do Rio Preto is the largest city in the state’s northwestern region, with approximately half a million inhabitants.

According to the survey, 32.9% of those tested in the under-40 age group were not immune to measles, compared with the 99% immunity observed in the over-50 age group.

The study was supported by São Paulo Research Foundation — FAPESP. The principal investigator was Maurício Lacerda Nogueira, a professor in the São José do Rio Preto Medical School and former chair of the Brazilian Society for Virology. The findings are published in Scientific Reports, an online journal owned by Springer Nature.

«Considering the total number with documented evidence of vaccination, 39.3% did not have immunity against measles, and 20.2% lacked antibodies against rubella. These percentages are sufficient to protect the population against rubella but not against measles. The combined vaccine against measles, mumps, and rubella [MMR] is part of the national vaccination calendar in Brazil,» Nogueira told.

The study, he added, suggests that there is a correlation linking the production of antibodies, vaccination, and exposure to the virus. The percentage of immune individuals among those aged more than 50 years who had been exposed to the virus throughout their lives was far higher than that among the younger age groups, even when they had been vaccinated.

«This relatively high seronegativity rate [lack of antibodies] needs to be investigated, but vaccination is the main weapon we have and absolutely mustn’t be discarded,» Nogueira said.

Measles were considered to be eradicated for years but re-emerged in several countries, including Brazil, after a decline in vaccination coverage. In the prevaccination period, it was a common disease in patients under 10 years of age, and despite a low mean mortality rate, it is estimated to have caused 5 million to 8 million deaths worldwide.

Measles is highly contagious, with a basic reproduction number (R0) of 12-18, meaning that each person with measles could transmit the virus to between 12 and 18 people in a totally susceptible population. For the sake of comparison, the novel coronavirus (SARS-CoV-2) has an R0 of 2-3, according to the World Health Organization (WHO).

«Measles can be controlled by vaccination programs that reach 95% coverage with two doses of the vaccine,» Nogueira said. «In addition, cases have to be properly identified, and measures must be taken to prevent transmission.»

According to a recently published study, the prevalence of measles in Brazil started to fall in 1998 as a result of vaccination. The last locally acquired case was reported in 2000.

An outbreak in 2013-15 produced 1,310 reported cases. The Pan American Health Organization (PAHO-WHO) implemented an action plan that was successful, and endemic transmission was considered eradicated in the Americas in 2016.

In 2017, however, cases were reported in the United States, Canada, Venezuela and Argentina. The disease recently began circulating in Brazil again, with 11,371 confirmed cases and 12 deaths in 2018-19.

«The spread of vaccine refusal has become a risk factor for measles outbreaks, and the WHO has identified vaccine hesitancy as one of the top ten global health threats in 2019,» the researchers stress in the Scientific Reports article.

###

About São Paulo Research Foundation (FAPESP)

The São Paulo Research Foundation (FAPESP) is a public institution with the mission of supporting scientific research in all fields of knowledge by awarding scholarships, fellowships and grants to investigators linked with higher education and research institutions in the State of São Paulo, Brazil. FAPESP is aware that the very best research can only be done by working with the best researchers internationally. Therefore, it has established partnerships with funding agencies, higher education, private companies, and research organizations in other countries known for the quality of their research and has been encouraging scientists funded by its grants to further develop their international collaboration. You can learn more about FAPESP at http://www.fapesp.br/en and visit FAPESP news agency at http://www.agencia.fapesp.br/en to keep updated with the latest scientific breakthroughs FAPESP helps achieve through its many programs, awards and research centers. You may also subscribe to FAPESP news agency at http://agencia.fapesp.br/subscribe.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

Essa notícia também repercutiu nos veículos:
Agência Brasil BOL Correio Braziliense online IstoÉ online IstoÉ Dinheiro online UOL G1 Rádio Milênio 105,9 FM Mídia Hoje Correio Popular (Campinas, SP) online Rádio 95.5 FM Arara Azul FM 96,9 Painel Notícias (Alagoas) Notícias da Sua Cidade Radio Top Xique FM MS Atual Rádio Hora Momento MT Cruzeiro FM 92.3 Jornal Nossa Voz AjuNews Meio Norte online Jornal Joseense News Portal da Enfermagem Tá Sabendo? Atemporal Mix Vale Notícias de Campinas Portal do Governo do Estado de São Paulo Mirassol Conectada Digital Rádio e TV Blog Jornal da Mulher Saber Atualizado Região Noroeste Notícias de Indaiatuba Jornal Ururau Gazeta Catarinense online Beto Ribeiro Repórter A Crítica (MS) online Catve Central das Notícias Diário do Cotidiano Diário Piauí Expresso Regional FA Notícias Gazeta Web Marechal News Jornal Integração Informe Baiano Informe Geral Itabuna Jornal de Piracicaba Jornal Dia Dia Primeira Edição Rádio Educadora de Sapeaçu Portal Lagartense.com.br Poliarquia Portal Agora no RS Portal de Notícias O Verídico Nitro News Brasil MidiaMax Mix Vale Novo Cantu Notícias O Bom da Notícia O Documento online Sistema Costa Norte de Comunicação Portal TopGyn Dinheiro Rural online Tribuna do Norte (Natal, RN) online Zero um informa BMNotícia Maranhão Negócios Planeta Osasco O Mato Grosso Jornal O Liberal (PA) online Portal Roma News A Gazeta News (MS) online Notícias Botucatu Nova Notícias Blog do Marcos Silva TN Online Jornal Extra de Alagoas online Portal 24h Ternura FM Painel Notícias O Imparcial (São Luís, MA) online Dourados Agora Z1 Portal de Notícias Acontece Botucatu O Liberal (PA) online Cassilândia Notícias Região Noroeste Noticias Noroeste online Novoeste Noticia Exata Liberdades Marechal online A Semana News Votunews Cariri em Ação Gazeta do Dia (Glória de Dourados, MS) Portal de Finanças Jornal Roraima Hoje ADET - Associação dos Deficientes de Tabira Portal F11 Leiamais.ba Jornal Maracaju Hoje (MS) online Sergipe Notícias Futblog do Sorriso Gazeta Minas a informação direta O Presente online Portal de Camaquã Gonzaga Patriota Jornal Folha de Videira online Caderno B Rondônia Dinâmica Jornal Preliminar Diariocrítico (Castilla y León, Espanha) Diário de S.Paulo online Diga Bahia Regione autonoma Valle d'Aosta (Itália) Brasília Agora Giro S/A Online ID News O Estado (CE) online Portal Giro Última Notícia (João Monlevade, MG) online Diário da Região (São José do Rio Preto, SP) online Amazonas Atual Na Mídia News Planeta online Itaporã News Tribuna (Ribeirão Preto, SP) online Diário do Aço online Rota do Sertão Preto no Branco Primeira Hora Jornal Grande Bahia Innaldo Sardinha Repórter 1 Diário do Poder BN - Bahia Notícias Notícias & Artigos Panorama Farmacêutico Cidade Satélite MSN (Colômbia) Portal Salvador Dez Jornal ZM Notícias online MSN O Observador online Correio Nogueirense Portal Marcela Rosa Espigão Alerta Roraima em Tempo online Universo Racionalista Dourados News Jornal Página do Estado Fato Amazônico Mix Vale Portal Tucumã MidiaMax Goias.me Pelo Mundo DF Portal Rondônia Jornal Floripa Portal Cidades Online Planeta Notícias News Atual MT Bahia Ligada Blog do Juares Rádio Jornal CGN Es 1 Campos 24 horas MSN (Argentina) Secretaria de Estado da Saúde de São Paulo Coluna Vip Studio Livre 98,5 FM (Rio Grande, RS) TV Assembleia - Assembleia Legislativa do Piauí (Alepi) Jornal Folha Noroeste Pfarma Giro de Notícia Rádio KB Portal Diário da Selva Brasil em Folhas online Tribuna Ribeirão online Rádio Web G Diário da Saúde Conexão Regional Ipiaú Urgente Rádio Cidadão FM Saense SouSorocaba Líder FM 98,3 (São José do Rio Preto, SP) Meu Mundo Digital Notícias do Nordeste Correio Popular (Ji-Paraná, RO) online Rádio Rota do Forró Nossa Rádio Tapirapé 98,5 FM Nh Tv Manaus Alerta GS News