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Gene Therapy Reverses Effects of Autism-Linked Mutation in Human Brain Organoids

Publicado em 04 maio 2022
The University of California San Diego (UCSD) study uses lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and test gene therapy tools. In a study published on May 02, 2022, in the journal Nature Communications, scientists at the University of California San Diego School of Medicine used human brain organoids to discover how a genetic mutation associated with a severe form of autism disrupts neural development. Using gene therapy tools to recover the [...]