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Washington, January 6 - Exercise may be the most powerful anti-aging intervention known to science and has been proven to protect against a wide array of diseases. However, while physical activity can improve health during aging, its beneficial effects inevitably decline. The cellular mechanisms underlying the relationship between exercise, fitness, and aging remain poorly understood. In a paper published in the Proceedings of the National Academy of Sciences, researchers at Joslin [...]

Scientists have uncovered a new mechanism that could help explain why some Covid infected people develop a potentially fatal systemic inflammation, according to a study. Researchers at the University of Sao Paulo (USP) in Brazil have found that severe COVID-19 is associated with an imbalance in an important immune system signalling pathway. The researchers detected "dysregulation", or a dysfunctional regulation, of the immune system mediated by adenosine triphosphate (ATP), one [...]

The process of selecting specialty coffee beans entails three kinds of inspection. Two are physical and involve samples of raw and roast coffee. The third is sensory and involves tasting the drink. Certification is provided by the Specialty Coffee Association of America (SCAA). In accordance with SCAA guidelines, coffee quality is measured on a decimal scale from zero to 100. A specialty coffee must score 80 or more. The grower sends a sample of raw beans to three cuppers (tasters), who [...]

“The human protein known as PCNA [proliferating cell nuclear antigen] interacts with the SARS-CoV-2 protein M [matrix], one of the molecules that make up the virus’s membrane and give it shape. The discovery itself shows one of the ways the pathogen manipulates cell function for its life cycle to proceed,” said Fernando Moreira Simabuco, a professor at UNICAMP’s School of Applied Sciences (FCA) in Limeira and principal investigator for the study, which was supported by [...]

A scientific article just published by four Brazilian and two American scientists reports gains in electric and thermal energy obtained when brewer’s spent grain (barley bagasse), an abundant waste produced by the beer industry, is treated with ultrasound before undergoing anaerobic digestion, a microbiological process involving consumption of organic matter and production of methane. Pre-treatment generated biogas with 56% methane, 27% more than the proportion obtained without use of [...]

The data they analyzed referred to some 11,500 athletes, including amateurs and high-performance professionals. The study was funded by FAPESP (projects 17/13552-2, 19/05616-6, 19/14819-8, and 20/04877-8). The results are reported in an article published in the British Journal of Sports Medicine. “We analyzed data from acute cases to appraise manifestations and severity, as well as persistent symptoms reported after the virus had been eliminated from the organism. This scope is more [...]

Scientists have long sought ways of influencing the functioning of the endocannabinoid system to help people lose weight. Rimonabant, a drug that acted as a cannabinoid receptor antagonist, was launched in 2006 but banned in Brazil owing to severe adverse side effects, including anxiety and depression, with suicidal tendencies in some cases. Studies have been performed since then to discover safer means to make the endocannabinoid system an ally of people who need to lose weight. Pep19 [...]

A new type of biofilm reactor adapted to Brazilian conditions and using polyurethane foam to lower costs can reduce the amount of nitrogen compounds in wastewater by as much as 70%, according to an article in Environmental Technology. The researchers who conducted the study developed a mathematical model to analyze and predict the nitrogen removal mechanism. The biofilm comprised bacteria that converted nitrogen compounds into nitrogen gas, which is environmentally harmless. The study was [...]

CINCINNATI, May 19, 2022 (GLOBE NEWSWIRE) — Blue Water Vaccines, Inc. (“BWV” or “Blue Water Vaccines” or “the Company”) a biopharmaceutical company developing vaccines, announces a collaboration with the multidisciplinary Center for R&D in Immunobiologics (“CeRDI”), an initiative of Instituto Butantan (“Butantan”). Through this partnership, Butantan, a leading Brazilian producer of immunobiologic products and vaccines, and [...]