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Worms, diseases that affect billions of people worldwide, have had little progress in clinical studies. One of the reasons this happens is because they reach the poorest populations, not attracting investment from pharmaceutical companies. The warning is in a study published in the magazine Drug Discovery Today by researchers from the University of São Paulo (USP) and the University of Guarulhos, which has the support of the São Paulo Research Foundation (FAPESP ). The work [...]

A group that brings together researchers from Brazil and Portugal has unveiled the molecular changes that indicate the resistance of head and neck tumors to cetuximab, one of the few therapies approved for this type of cancer. About 60% of patients do not respond well to treatment. With the results, published in the review cells, it is expected that doctors will soon be able to predict which patients will or will not respond to the treatment, considered expensive. Based on the [...]

A study developed by researchers from the departments of physiotherapy (DFisio) and gerontology (DGero) of UFSCar has identified that there is a relationship between low blood levels of vitamin D and the risk of developing functional disability in activities. instruments of daily life (IADL) in Men. The research was developed by Mariane Marques Luiz, currently a doctoral student in physiotherapy at UFSCar, under the supervision of Tiago da Silva Alexandre, professor at DGero at UFSCar and [...]

High-speed processing of viral genetic material from the first confirmed case in Brazil was possible thanks to the adaptation of an existing technique Researchers at the Joint UK-Brazil Center for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology (CADDE) concluded in just 18 hours the complete genome sequencing of the monkeypox virus (MPXV) isolated from the first patient diagnosed with monkeypox confirmed in Brazil. The high speed in the processing of viral genetic material was [...]

At USP’s IQ (Institute of Chemistry), research has identified genes associated with the proliferation of cancerous tumors of the pancreas, which are highly resistant to treatment. Using computer techniques, the scientists were also able to assign possible functions to the genes, such as the growth and migration of tumor cells, to be confirmed by laboratory experiments. The results of the work will help define new targets for the treatment of cancer, as well as markers of residual or [...]

A material with the potential to eliminate the COVID-19 virus on surfaces and, in addition, to combat the inflammatory complications of the disease live was described by researchers from Functional Materials Development Center (CDMF) em article published in the journal Scientific reports. The group was based on a study published in 2020, in the magazine nano todaywho hypothetically pointed to the therapeutic potential of nanoceria [...]

The reappearance of diseases hitherto controlled by vaccination is a specter that haunts countries that record a steady decline in vaccination coverage, such as Brazil.1. After an outbreak of the disease recorded in the country throughout 2018, the country lost the certification of measles-free country granted by the Pan American Health Organization (PAHO) the following year. Since then, cases of measles have been reported every year in Brazil, even during the coronavirus pandemic.1. With [...]