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The COVID-19 virus hijacks the machinery of testicular cells that produce the hormone testosterone in order to replicate. It also appropriates the metabolic pathways of these cells and cholesterol, a precursor of testosterone, thereby altering lipid metabolism for its formation. This was verified in a study conducted in Brazil by researchers from the Araraquara School of Dentistry at São Paulo State University (FOAr-UNESP), in partnership with the Ribeirão Preto School of Medicine [...]

A study conducted at the Botucatu School of Medicine at São Paulo State University (FMB-UNESP) in Brazil has shown that low-dose vitamin D supplementation can increase the effectiveness of chemotherapy treatment in women with breast cancer. The results suggest that the substance could be an alternative to hard-to-access drugs that also aim to increase the response to chemotherapy. The research,supported by FAPESP, involved 80 women over the age of 45 who were about to start treatment [...]

Alcohol consumers have been issued a warning as new research shows heavy alcohol intake increases the risk of brain damage by 133 per cent. A new study published in Neurology has revealed that moderate, heavy, and former heavy drinkers all showed an increased risk of hyaline arteriolosclerosis, and thickening and narrowing of blood vessels. Heavy and former heavy drinkers also showed an increased risk of neurofibrillary tangles associated with Alzheimer's disease. The [...]

A Greater mouse-eared bat is seen at the vault of an old brewery in Frankfurt an der Oder, eastern Germany, on January 17, 2014. Once a year, conservationists inspect the vault to count the animals. Around twelve bat species hibernate in the protected cellar. A new coronavirus which may be able to spread to humans has been discovered by Chinese-linked scientists. Brazilian researchers and colleagues from Hong Kong detected a strain in bats that is closely related to MERS, which kills [...]

From a study that analyzed brain images of more than 2,500 people with Parkinson's disease in 20 different countries, scientists were able to identify patterns of neurodegeneration and create metrics for each of the five clinical stages of the disease. The work, published in NPJ Parkinson's Disease, represents a leap forward in the understanding of the disease. The analysis and volume of data obtained in the study could lead to important developments, not only in terms [...]

Medical technicians are looking at the microscope inside the hospital laboratory. Before antibiotics, infectious diseases were some of the biggest killers in the world. Developing these lifesaving drugs enabled humanity to combat illnesses and significantly extend the average lifespan by decades—but that could be changing. In recent times, some diseases have developed a resistance to the healing power of antibiotics and could pose a serious threat to human life if urgent action [...]

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia (FCD), a malformation of the cerebral cortex that leads to drug-resistant epilepsy. These cases are most common in children and adolescents, accounting for up to 50% of epilepsy surgeries in this age group. With the atlas, it was possible to characterize the different cell types present in the brain lesion and determine which ones are involved in the disease. The [...]

A new study by a team of researchers from the UK and Brazil has revealed a strong connection between childhood trauma and the development of psychiatric disorders in adolescents living in low-and middle-income countries. The research findings are based on the 2004 Pelotas Birth Cohort, Brazil, which has tracked more than 4,000 children born in Pelotas, a city in the southern state of Rio Grande do Sul, from birth to age 18. Published in The Lancet Global Health, the study looked at how [...]

Engaging in a specific type of exercise regularly could potentially lower our risk of a devastating condition later in life, according to a new study. Research has found a connection between aerobic exercise and a decreased likelihood of developing Alzheimer's disease, the most prevalent form of dementia in the UK. This progressive condition gradually affects multiple brain functions over many years, leading to memory loss and symptoms such as confusion and speech problems. While the [...]