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A study conducted at the University of São Paulo suggests that tissues specializing in saliva production and secretion serve as reservoirs for SARS-CoV-2, magnifying its infectious potential (electron microscope image showing novel coronavirus inside salivary glands; credit: Bruno Matuck/USP) In Brazil, researchers at the University of São Paulo’s Medical School (FM-USP) have discovered that SARS-CoV-2 infects and replicates in the salivary glands. Analysis of samples from [...]

A study conducted in the Una Biological Reserve in the state of Bahia, Brazil, shows that in a habitat with high hunting pressure the risk of predation has such a significant impact on the behavior of the Yellow-breasted capuchin monkey Sapajus xanthosternos that it even avoids areas offering an abundant supply of plant biomass and invertebrates, its main sources of food. An article reporting the findings of the study is published in the American Journal of Primatology. “Many theories [...]

Brazilian researchers have simultaneously demonstrated the mechanism linking high blood pressure to elevated intracranial pressure, validated a non-invasive intracranial pressure monitoring method, and proposed a treatment for high blood pressure that does not affect intracranial hypertension. The study was supported by FAPESP and involved collaboration between researchers at São Paulo State University (UNESP) and Brain4care, a startup based in São Carlos. It could [...]

The long and post-acute effects of COVID-19 will be the theme of the next FAPESP COVID-19 webinar that will be held on June 2nd. COVID-19 is a novel disease which is revealing unprecedented challenges. While many patients with symptoms fortunately can survive acute disease, a substantial cohort undergoes a sustained clinical picture, exhibiting a subacute stage or “long” COVID-19. These patients persist with (ocasionally severe) fatigue, joint and muscle pains, neuro-psichyatric [...]

Inclusion of soybean and linseed oils in the diet of dairy cows made the fatty acid content of their milk even healthier for human nutrition. It also increased the proportions of omega-6 and omega-3, which in the right balance play a key role in preventing cardiovascular diseases, for example, as well as chronic inflammation and some kinds of cancer. Cardiovascular diseases are one of the world’s main public health problems. In Brazil, they are among the foremost causes of death. Each [...]

Aging entails a loss of muscle mass and strength, which in some cases impairs mobility, hinders walking or performance of day-to-day tasks, and exposes the elderly to the risk of falls and hospitalizations. In clinical practice, handgrip measurement is the most widely used method to identify loss of overall muscular strength in older people. Values below 26 kg for men and 16 kg for women have for some time been considered an indication of risk-associated weakness, but these parameters are [...]

Entitled “Education: COVID-19 and social inequalities”, a March 03 webinar promoted by FAPESP, the São Paulo Research Foundation, will be gathering experts on education to explore how the pandemic has impacted education in different national contexts. They will discuss the challenges associated with the implementation of responses by the educational systems in face of structural inequalities. The webinar will be broadcasted from 2 to 4 p.m (UTC – 03:00). FAPESP invites [...]

Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time – around three to five weeks – to have the desired effect. A group of researchers affiliated with the University of São Paulo (USP) in Brazil set out to tackle the second problem by using epigenetic modulators to try to “erase” the consequences of stress. [...]

An international group of researchers have discovered that inhibiting AHR (aryl hydrocarbon receptor), a protein with roles in regulating immunity, stem cell maintenance and cellular differentiation, enables the immune system to combat replication of zika virus in the organism far more effectively. In experiments performed at the University of São Paulo’s Biomedical Sciences Institute (ICB-USP) in Brazil, the antiviral therapy proved capable of preventing the development of [...]