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Researchers at the University of São Paulo (USP) in Brazil have discovered that two osteoporosis drugs (etidronate and tiludronate) may combat diseases caused by iron accumulation in the body. In tests conducted on human cells, the drugs bound to excess iron, reduced oxidative stress, and prevented cell damage. The study was published in the journal BioMetals. “Currently, only three drugs are approved to treat iron overload, known as chelators. They bind to the metal and thus [...]

High glucose levels could serve as a biomarker indicating a worse outcome in patients who have experienced their first acute myocardial infarction, according to researchers in Brazil. The study demonstrated that glycaemic variability, particularly glycaemic delta, is associated with the size of the infarction and a reduction in left ventricular ejection fraction (LVEF). LVEF shows the strength of the heart’s contraction; if it is reduced, heart failure may result. To evaluate muscle [...]

Excessive physical exercise, especially without adequate rest, can damage the human body in various ways. In severe cases, it can progress to overtraining syndrome, which is characterized by decreased performance and appetite, chronic fatigue, muscle pain, increased injuries, and changes in the immune system and metabolism. A study published in the journal Molecular Metabolism points to excessive protein expression as the cause of the syndrome. A research team from the State University of [...]

A study conducted by researchers from the Federal University of São Carlos (UFSCar) found that 72.5% of young Brazilian women suffer from symptoms such as itching, discharge, and pain during intercourse. The study, which included 313 volunteers in their 30s, showed that, although these symptoms negatively affect quality of life and sexual health, they have largely been normalized. The data were published in the Brazilian Journal of Physical Therapy. According [...]

One of the pillars of the Brazilian economy and one of the sectors responsible for the highest greenhouse gas emissions, beef production in Brazil, as it is currently practiced, emits more than twice the limit needed to meet international environmental targets. This is one of the conclusions of a study published in the journal Environmental Science and Pollution Research. The work includes an evaluation of projected emissions scenarios, along with an economic assessment. The researchers [...]

A study analyzing data from nationally representative dietary surveys and mortality data from eight countries (Australia, Brazil, Canada, Chile, Colombia, Mexico, United Kingdom, and United States) shows that premature deaths attributable to consumption of ultraprocessed foods (UPFs) increase significantly according to their share in individuals’ total energy intake. The new study, appearing in the American Journal of Preventive Medicine, published by Elsevier, reinforces the call for [...]

High blood pressure (hypertension) causes thickening of the blood vessels and hardening of the arteries (arteriosclerosis). A study conducted by Brazilian researchers has shown for the first time that a similar phenomenon occurs in the lungs. High blood pressure hardens the bronchi and increases airway resistance, impairing respiratory capacity. The study sample comprised 731 men and women over 60, both with and without high blood pressure. It was designed to investigate the effects of [...]

A naturally occurring molecule could help to prevent – and even treat – influenza, according to a new study published in the journal Gut Microbes. The molecule, indole-3-propionic acid (IPA), occurs naturally in the gut of mammals and may play a protective role in the body’s response to infection. The findings were published by scientists at the State University of Campinas (UNICAMP) in São Paulo state, Brazil, working with a team at the Pasteur Institute in Lille, [...]

According to an article published in the journal Clinical Oral Investigations, people who suffer from post-traumatic stress disorder (PTSD) often report constant clenching or grinding of the teeth during the day, a condition known as awake (or diurnal) bruxism. Its prevalence in the general population varies from 8% to 30%. The study, which included clinical examination of 76 patients and controls, highlights the importance of collaboration by dentists and psychiatrists to diagnose both health [...]