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Study helps understand why kids of obese mothers may be susceptible to metabolic diseases
Publicado em 27 janeiro 2021
A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop metabolic disease during their lifetime, as suggested by previous research.
According to the authors, “transgenerational transmission of metabolic diseases” may be associated with Mfn2 deficiency in the mother’s oocytes (immature eggs). Mfn2 refers to mitofusin-2, a protein involved in the regulation of [...]
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Inflammation caused by scorpion venom should be blocked immediately, study shows
Publicado em 21 janeiro 2021Tityus serrulatus, the Yellow scorpion, causes more deaths than any other venomous animal in Brazil. Its sting can induce heart attack and pulmonary edema, especially in children and the elderly. According to the Brazilian Health Ministry, more than 156,000 cases of scorpion envenomation, 169 fatal, were reported in the country in 2019. Researchers at the University of São Paulo (USP) have demonstrated for the first time that in severe cases of scorpion envenomation a systemic [...]ver notícia -
Scientists study use of abundant enzyme in tumor cells to monitor cancer treatment
Publicado em 12 janeiro 2021The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential. It is also known to perform important functions in cells under normal conditions, participating in both the proliferation process and the regulation of intracellular systems. Research continues on its role in cancer progression. In Brazil, a group of researchers at the University of [...]ver notícia -
Scientists seek faster route to treat depression
Publicado em 04 janeiro 2021Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time—around three to five weeks—to have the desired effect. A group of researchers affiliated with the University of São Paulo (USP) in Brazil set out to tackle the second problem by using epigenetic modulators to try to “erase” the consequences of stress. [...]ver notícia