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Lesson: The amino acid Taurine may be a comforting partner for aging (71 notícias)

Publicado em 06 de julho de 2022

By processing the oxygen we breathe and the meals we eat every day to outlive, our cells produce poisonous merchandise, referred to as “free radicals”. Some of those molecules carry out necessary capabilities for the physique, however in extra they’ll injury the interior buildings of cells, disrupting the operate and properly -being of the cells. continual loss of life. This course of is called oxidative stress.

Our physique accommodates a true wealth of antioxidant enzymes to assist the assorted response occasions to be balanced. However, as we become old, these administration practices develop into much less and fewer frequent. According to a research revealed within the journal The meals supplementing meals with amino acid supplementation is a good food plan technique to keep away from stress.

The research was performed on the University of São Paulo (USP) with 24 members, between 55 and 70 years previous, randomly divided into two teams. Half consumed three capsules each day with 500 milligrams of taurine every (1.5 grams per day) for 16 weeks. Some merely swallowed capsules containing a placebo. Participants and researchers didn’t know who the group was.

Oxidative stress signs had been assessed in blood samples collected earlier than and after the intervention. One of probably the most optimistic outcomes was an virtually 20% improve within the focus of the enzyme superoxide dismutase (SOD) within the group handled with taurine – within the decreased management group this enzyme is 3.5%. As defined by the authors, SOD protects the cell from opposed reactions of superoxide radicals.

“By stopping the buildup of free radicals that happen as we age, we may stop coronary heart illness, diabetes and hemorrhage, amongst different continual ailments. continued ”, opinions Ellen de Freitas, professor on the Ribeirão Preto School of Physical Education and Sport (EEFERP-USP) and coordinator of a venture supported by FAPESP.

According to the researcher, within the scientific literature there are few research on the impact of taurine within the context of aging. “This is a very early research, which goals to analyze the optimum dose and unwanted effects – not present in any of the members.”

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Taurine is a nutrient present in meals similar to fish, rooster, turkey, pink meat and seafood. It is of course fashioned in sure tissues of the human physique, particularly the liver, and is necessary for the functioning of the central nervous system, illness, imaginative and prescient and productiveness.

For greater than a decade, the group co -sponsored by Freitas has been learning the antioxidant and anti -inflammatory results of taurine – first in excessive -performance athletes, adopted by overweight athletes, and doses are between 3 and 6 grams per day. “The outcomes present that, with the addition of this amino acid, oxidative stress can be managed in these folks. The secure dose is just too low.” , says Freitas.

The first consideration was to judge the impact of taurine and bodily exercise with each interventions. Physical exercise is alleged to be one of many major instruments to change the degrees of oxygen and antioxidant substances within the physique, and in the correct dose, it’s believed that it may possibly improve the advantages. of taurine. However, with the onset of the illness and the truth that members from one group had been extra more likely to develop infections from COVID-19, it was determined to take care of the dietary element of the research, and may be seen remotely.

In addition to SOD, two different indicators of oxidative stress had been analyzed: the antioxidant enzyme glutathione reductase (GR), which was considerably decreased in each teams, and the organic indicator of oxidative stress referred to as which is malondialdehyde (MDA), which elevated by 23% in management. group and decreased by 4% within the common variety of ladies who took taurine.

“It’s a disappointing end result, however we consider it can be extra necessary with a larger dose of taurine”, Freitas opinions.

For Gabriela Abud, presently a medical scholar on the Faculty of Medicine of Ribeirão Preto (FMRP-USP) and the primary creator of the article, the modifications within the food plan of volunteers in the course of the first months of social isolation have affected the outcomes of organic analyzes. .

“In addition to oxidative stress indicators, we analyzed the focus of minerals similar to selenium, zinc, magnesium and calcium, that are necessary for the operate of those enzymes. [que indiretamente ajuda a eliminar o peróxido de hidrogênio do organismo] and can be decreased in two teams ”, says Abud.

According to Freitas, icing on the cake is simply “icing on the cake” that doesn’t work wonders. “A wholesome way of life, with a balanced food plan and common train, is necessary for the anti-aging impact to happen.”

In the next research, the group advised that overweight ladies, between the ages of 60 and 75, had sarcopenia – a situation characterised by lack of muscle mass and contact with irritation. “There is a inhabitants that’s at excessive danger of growing issues. We provide bodily coaching that includes supplementing every day with 3 grams of taurine and monitoring the modifications that end result from these actions.” , Freitas says.

It is truthful to say that the advantages and dangers of including meals to taurine are nonetheless being researched. The consumption of dietary supplements shouldn’t be carried out with out the assistance of a medical skilled.

The article Taurine as a treatment for previous age? A medical trial of taurine antioxidant exercise in ladies 55 to 70 years of age It can be learn at: www.sciencedirect.com/science/article/abs/pii/S0899900722001198# !.