A survey conducted by scientists from the Faculty of Medicine at the University of Sao Paulo (USP) in Ribeiro Preto shows that Combine aerobic exercise with the use of the drug lasartan. For hypertension, Increased heart benefits In men
Scientists have shown that physical activity increases heart rate in patients with hypertension who take lucartan.
Heartbeat variables describe the oscillations that occur at intervals between consecutive heartbeats. A high variability means good adaptation of the body, meaning it is seen in healthy people. Low variability indicates the opposite – and appears in people with high blood pressure.
“The more variable the system, the more it changes. This demonstrates a more efficient ability to adapt,” said Hugo Celso Dotra de Souza, senior author of the research and professor at the USP School of Medicine in Ribeirão Preto. Explained g1.
This is important because high blood pressure is not only related to high blood pressure within the blood vessels but also to a series of cardiovascular problems – one of which is the change of heart rate in particular.
Lasartan is effective in reducing this pressure, but also in its use Frequency variability is low.. In the study, variability increased when people with high blood pressure and taking losartan began to exercise.
“In addition to further reducing pressure, frequency regulation improves. [com o exercício físico] – Close to normal. It does not cure, but eliminates the comorbidities that accompany it. High blood pressure is a major cause of heart failure – a major cause of early death. ”
The study, published in the journal Clinical and Experimental Hypertension, involved 32 volunteers, all men and women between the ages of 40 and 60. Half of them did not have high blood pressure and were not taking any medication, and the other half were suffering from high blood pressure and were taking losartan.
Both groups walked 45 minutes three times a week for 16 weeks (approximately 4 months).
Losartan alone was able to lower blood pressure – bring it back to normal – but without exercise, cardiac autonomic control – among other things, rate change – remained poor.
“Medication alone cannot properly restore heart rate. It is important and necessary to lower blood pressure, but medication alone is not enough. Exercise completes the effect,” said Hugo Celso de Souza to Agência. FAPESP strengthened.
The agency said scientists are also working on a paper that compares losartan to enalapril maleate, the agency said.
“Exercise is important, and it has been seen as a kind of magic pill. However, we need to understand what it actually does in the body so that who knows what its pharmacological effects will be in the future.” Can try to imitate “, Souza recalled.
A separate study is being conducted with women – because ovarian hormones interfere with cardiac function.
“In mice, we removed the ovaries and automatically increased the amount of fibrosis in the heart over the weeks. Not only do these ovarian hormones regulate heart structure. [como] They also participate in the regulation of hemodynamics as a whole. There is a fundamental effect, “the researcher explained. g1.
“It makes sense, because women of reproductive age are ‘protected’ by ovarian hormones – so much so that, before menopause, there are more women than men with heart disease. Women after menopause.” [não só] Leaving behind the number of people suffering from heart disease due to hormones, ”he pointed out.