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A group of researchers in Brazil and the UK have developed a method to track seroprevalence in real time. An article in the journal eLife shows how this was done in the case of SARS-CoV-2, providing a "portrait" of the first year of COVID-19 in Brazil. An article published in the journal eLife reports a study in which researchers concluded that the proportion of the population previously infected by SARS-CoV-2 (infection-induced seroprevalence) can be estimated using blood donation [...]

MONDAY, Dec. 19, 2022 (HealthDay News) -- One way to maintain muscle strength with age: Get enough vitamin D. Researchers in Brazil and the United Kingdom found that older folks who were deficient in the vitamin increased their risk of losing muscle strength by 78%. "Vitamin D is known to participate in various functions. …," said study co-author Tiago da Silva Alexandre, a professor of gerontology at Federal University of São Carlos. "Its many roles [...]

December 14, 2022 by Maria Fernanda Ziegler, FAPESP Religion influences secondary school students' understanding and acceptance of evolutionary theory, but social and cultural factors such as nationality, perceptions of science and household income are more influential, according to a study involving 5,500 Brazilian and Italian students aged 14-16. An article on the study is published in the journal PLOS ONE The participants were asked to agree or disagree with a number of statements [...]

A new study describes how the functioning of RNA changes in cells infected by SARS-CoV-2 , the COVID-19 virus. The findings provide clues as to how different variants can escape the immune system, and serve as a basis for the development of novel treatments. For the first time, scientists have shown that infection by SARS-CoV-2, the virus that causes COVID-19, changes the functioning of host cell RNA. The researchers, from the Federal University of São Paulo (UNIFESP) in Brazil, [...]

Visceral adipocytes, or tissues where fat is stored as an energy source, were infected, they produced a larger amount of pro-inflammatory cytokines, which warned the immune system of the existence of a threat to be combated. Washington: Scientists have found that the fat around the liver, intestines and other organs, or visceral fat , contributes more towards severe Covid-19 than does subcutaneous fat, or fat under the skin as in 'love handles', according to a study.Visceral fat is [...]

Scientists have found that the fat around the liver, intestines and other organs, or visceral fat, contributes more towards severe COVID-19 than does subcutaneous fat, or fat under the skin as in “love handles”, according to a study. Visceral fat is usually considered a risk factor for cardiovascular disease, diabetes and high blood pressure. The researchers at the State University of Campinas (UNICAMP) and the University of Sao Paulo (USP) also found that when visceral [...]

Trypanosoma cruzi, affects some 8 million people worldwide. More than a third develop severe heart or digestive problems with a heightened risk of death. The process that leads to this clinical condition is not completely understood. An article published in the journal Biomedicines describes a study led by Brazilian researchers showing that mutations occur in the mitochondrial genes of patients with Chagas disease megaesophagus, a disorder in which the esophagus dilates and loses motility. [...]

Rapid, cheap and accurate tests continue to be essential for epidemiological surveillance and for health services to monitor and contain the spread of SARS-CoV-2. Brazilian scientists have contributed to endeavors in this field by developing an electrochemical immunosensor that detects antibodies against the virus. The innovation is described in an article published recently in the journal ACS Biomaterials Science and Engineering. In search of a novel diagnostic method, the group opted [...]

In Brazil, a group of researchers has reported the largest outbreak to date of COVID-associated candidemia caused by the same drug-resistant strain of Candida parapsilosis, a fungus that invades the bloodstream and can lead to death. The outbreak occurred in 2020-21 in an intensive care unit (ICU) at a tertiary referral hospital in Salvador, Bahia state, during one of the peaks of the COVID-19 pandemic. In an article published in the journal Emerging Microbes and Infections, the [...]