HealthUnlocked (Reino Unido)

Innovative cancer treatment found to be a promising approach to the control of fungal infections

Publicado em 05 março 2021

An innovative cell-based treatment for cancer has been found promising for the control of infections caused by fungi. A study published in the journal Cytotherapy reports that the use of CAR (chimeric antigen receptor) T-cells programmed to “recognize” Cryptococcus spp. fungi was effective in combating infection in vitro and in mice.

C. gattii and C. neoformans are present in soil with dead organic matter and places contaminated by the droppings of pigeons and other birds. They cause systemic mycoses in the human organism. They can infect the lungs and central nervous system, causing meningitis or meningoencephalitis. The symptoms vary according to the site of the infection, which can be fatal. Transmission occurs by inhalation of the fungi.

Cytotherapy. Study Paper: