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Zika virus infection throughout being pregnant could cause extreme abnormalities within the fetus, together with malformations comparable to microcephaly. In a small proportion of circumstances, the disease might result in miscarriage and perinatal loss of life. A community of greater than 30 Brazilian researchers got down to discover the causes of those issues with the assist of FAPESP and obtained important outcomes after half a decade of onerous work. A paper describing their findings has [...]

There are greater than 70 species of flavivirus, and lots of trigger illnesses in people and animals, together with dengue, Zika, and yellow fever viruses. A novel flavivirus identification take a look at that’s each quick and delicate has been validated in Brazil by Mariana Sequetin Cunha and collaborators on the Adolfo Lutz Institute, a number one epidemiological surveillance laboratory that studies to the São Paulo state authorities. An article on the subject has been revealed [...]

Arthritis impacts virtually 2% of the world’s inhabitants, or some 150 million individuals, and presently, there isn’t any utterly efficient remedy for this continual disease. A brand new molecule developed within the laboratory has been proven to have potential therapeutic results. Tested in mice with genetically induced arthritis, it suppressed the inflammatory course of, lowering each irritation and joint tissue put on and tear. Arthritic mice handled with the substance displayed [...]

Oxytocin, produced by the hypothalamus and typically often called the “love hormone” for its involvement in pair bonding and orgasm, generally is a robust ally within the management and prevention of osteoporosis, in line with a examine by scientists at São Paulo State University (UNESP) in Brazil. The examine confirmed that when administered to feminine rats on the finish of their fertile interval, the hormone reversed precursors of osteoporosis, resembling lowered bone [...]

Photodynamic remedy may be an environment friendly ally to fight secondary infections in COVID-19 sufferers. Use of the approach, which mixes gentle and a photosensitizing chemical substance to kill microorganisms within the respiratory tract, is advocated as a complementary remedy in a function revealed in Photodiagnosis and Photodynamic Therapy and written by researchers affiliated with the Optics and Photonics Research Center (CEPOF ) in São Carlos, state of São Paulo, [...]

An international group of researchers have discovered that inhibiting AHR (aryl hydrocarbon receptor)—a protein with roles in regulating immunity, stem cell maintenance and cellular differentiation—enables the immune system to combat replication of zika virus in the organism far more effectively. In experiments performed at the University of São Paulo’s Biomedical Sciences Institute (ICB-USP) in Brazil, the antiviral therapy proved capable of preventing the development [...]

Researchers at Biolinker, a biotech startup primarily based in São Paulo, Brazil, are creating a low-cost high-performance COVID-19 diagnostic take a look at utilizing solely domestically sourced inputs. Biolinker is incubated on the University of São Paulo’s Center for Innovation, Entrepreneurship and Technology (CIETEC), collectively run by the University of São Paulo (USP) and the Nuclear and Energy Research Institute (IPEN). The challenge was one of many first [...]

Researchers at São Paulo State University (UNESP) in Araçatuba, Brazil, have developed a computational tool that acts like a "COVID-19 accelerometer," plotting in real time the rate at which growth is accelerating or decelerating in more than 200 countries and territories. Available free of charge online, the application automatically loads the most recently notified case numbers from the European Center for Disease Prevention and Control (ECDC), updated daily, and [...]

Immune system cells within the blood of breast most cancers sufferers bear alterations early within the disease course, in response to a examine printed within the journal Clinical & Translational Immunology. The authors consider that this discovery could contribute to the early identification of aggressive tumors and assist improve personalised immunotherapy methods sooner or later. The examine was performed whereas Rodrigo Nalio Ramos, who was doing a doctoral analysis internship at [...]