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A drug carrier able to reach the brain, bind to an aggressive type of tumor called glioblastoma multiforme, and release a chemotherapeutic agent has been tested for the first time by Brazilian researchers. According to an article published in the International Journal of Pharmaceutics, the potential treatment was shown to be effective in isolated cells and animal models thanks to a combination of nanotechnology, chemotherapy and a monoclonal antibody. Glioblastoma multiforme accounts for 60% [...]

Weak muscles and abdominal fat are a dangerous combination for older people who have difficulty walking. A study conducted by researchers at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, in partnership with colleagues at University College London (UCL) in the UK, points to a significant loss of gait speed in older people with these two physical traits. A slower gait is a natural outcome of the aging process, but mobility problems can result if [...]

Newborn infants and babies aged up to three months should be stimulated to manipulate objects and observe adults performing everyday tasks. This incentive helps their social, motor and cognitive development, researchers note in an article published in the May 2021 issue of the journal Infant Behavior & Development. According to the authors, from the earliest age babies watch adults carrying out activities such as handling utensils and putting them away in drawers or closets. They should [...]

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a certain protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible for producing a cytokine that triggers a cascade of events resulting in the onset and progression of the disease. The knowledge of how the disease can be resolved in cell cultures and animals will form a basis for the research and development of a drug to control [...]