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Brazilian scientists have demonstrated that a new peptide has powerful anti-obesity properties in a rodent study and may help develop a potent weight loss drug. In a mouse model study conducted at the University of São Paulo (USP), researchers have shown that a synthetic molecule – known as Pep19 – effectively influences the endocannabinoid system, which is essential for regulating and balancing metabolic processes, such as appetite, fat breakdown (lipolysis), and energy [...]

A new study showed an association between child poverty and a heightened propensity to develop externalising disorders during adolescence and early adulthood. According to psychiatrists, externalising disorders are characterised by poor impulse control, rule-breaking, aggression, impulsivity, attention deficit and hyperactivity, amongst other forms of behaviour. The researchers analysed the impact child poverty has on the development of mental disorders. The study was published in [...]

Contracting COVID-19 during pregnancy can increase a woman’s risk of developing pre-eclampsia, researchers have demonstrated. A review of scientific literature by researchers in Brazil has shown that pregnant women infected by SARS-CoV-2 have a higher risk of developing pre-eclampsia, which can cause serious harm to both the mother and baby. The findings of the review feature in the journal Clinical Science. Pre-eclampsia is a condition that affects some pregnant women, usually during [...]

A combination of inflammatory cytokines in the blood and regular cannabis use, or use at a young age, can increase the chances of developing psychiatric disorders, researchers have demonstrated. A first-of-its-kind study by researchers at the University of São Paulo‘s Ribeirão Preto Medical School (FMRP-USP) in Brazil found that individuals exposed to a combination of these two factors – the presence of pro-inflammatory cytokines in the blood and [...]

A new study has developed a novel, wearable rehabilitation device that uses virtual reality to increase brain connectivity. The study, carried out at one of the Research Centers supported by FAPESP, has resulted in the development of the virtual reality (VR) device and has been recognised as ‘outstanding’ by the 20th International Conference on Computational Science and its Applications. Today, many rehabilitation programmes incorporate VR as a complement to [...]

Scientists have identified a non-inherited mutation in blood cells from a patient with GATA2 deficiency that may have prevented bone marrow failure and other clinical manifestations. For the first time, researchers at the Center for Cell-Based Therapy (CTC) in Ribeirão Preto, Brazil, have identified a non-hereditary mutation in blood cells from a patient with GATA2 deficiency. GATA2 deficiency is a rare autosomal disease caused by inherited mutations in the gene that encodes [...]

A more effective and less expensive pneumonia novel vaccine is on the horizon thanks to new research. The novel vaccine against pneumonia, developed by researchers at the Butantan Institute (Brazil) and Boston Children’s Hospital , part of the Harvard Medical School (USA), is now being tested in human patients. According to the researchers the innovation is capable of providing protection against all serotypes of the bacterium Streptococcus pneumoniae. The research was led by Cerqueira [...]

Larvae of a fungus gnat found in Iporanga, São Paulo State, Brazil, have bioluminescent properties previously observed only in species native to North America, New Zealand and Asia; this study paves the way for new biotech applications Brazilian researchers have discovered a new species of fungus gnat (Keroplatidae) whose larvae emit blue light. The small fly inhabits an Atlantic Rainforest reserve in São Paulo State. This is the first record of a blue bioluminescent species in [...]

A survey of almost 3,000 people in Brazil who have experienced first-episode psychosis has found that young men, ethnic minorities and people living in socioeconomically disadvantaged areas are more likely to suffer from the common symptoms. First-episode psychosis is defined as the first manifestation of one or more severe mental disorders including bipolar affective disorder, schizophrenia and depression with psychotic symptoms such as delusions, hallucinations and cognitive [...]