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A study conducted by the Molecular Oncology Research Center (CPOM) at Hospital de Amor in Barretos (formerly Barretos Cancer Hospital) in the state of São Paulo, Brazil, has identified possible biomarkers that could guide the development of more personalized therapies for pediatric germ cell tumors (GCTs). São Paulo Research Foundation Sep 18 2025 A study conducted by the Molecular Oncology Research Center at Hospital de Amor in Barretos in the state of São Paulo, [...]

An international team of researchers has discovered a new component of the peripheral nervous system that acts by increasing energy metabolism in the body. São Paulo Research Foundation Nov 25 2024 The finding paves the way for the development of simpler and cheaper drugs to control obesity and weight gain, regardless of the amount of food ingested. Since this new component does not act on the brain, but on the periphery of the organism, it opens up a new perspective for the [...]

What is Klebsiella pneumonia? A WOMAN who was admitted to hospital with a UTI died after contracting a dangerous new strain of superbug. But the new strain, a "hypervirulent" version, is considered even more dangerous, making even healthy people seriously ill.The bacterium found in the woman was found to be so versatile it adapted to changes in treatment, "easily acquiring resistance mechanisms not targeted by existing drugs either single or in combination", said Nilton [...]

During the COVID-19 pandemic, above all before vaccines were available, an alarm was sounded regarding a possible correlation between severe cases of COVID-19 in pregnant women and preeclampsia, a condition characterized by high blood pressure (hypertension) in the expectant mother and high levels of protein in her urine (proteinuria). It can entail dangerous complications for mother and baby.  Preeclampsia was more frequent in pregnant women infected by SARS-CoV-2 and was associated [...]

A study conducted at the Center for Research on Redox Processes in Biomedicine (Redoxoma) helps understand how high blood sugar (hyperglycemia), one of the manifestations of diabetes, can cause thrombosis. The findings, reported in an article published in the Journal of Thrombosis and Haemostasis, can contribute to the development of strategies to prevent cardiovascular dysfunction in diabetics. "The leading causes of death in Brazil and several other [...]

A study of patients with metastatic lung cancer by researchers based in Brazil and the United States has found that their performance in simple physical tests such as sitting down, standing and walking can help physicians arrive at a prognosis and approach to treatment. São Paulo Research Foundation Oct 22 2024 The findings also included identification in the volunteers' blood plasma of two substances – serine and M22G – with the potential to become biomarkers capable [...]

High blood pressure (hypertension) causes thickening of the blood vessels and hardening of the arteries (arteriosclerosis). A study conducted by Brazilian researchers has shown for the first time that a similar phenomenon occurs in the lungs. High blood pressure hardens the bronchi and increases airway resistance, impairing respiratory capacity. Fundação de Amparo à Pesquisa do Estado de São PauloOct 17 2024 High blood pressure causes thickening of the blood [...]

A self-proclaimed Brazil-Italy collaboration enthusiast, researcher Laura Bolognesi created the B2AlzD2 Joint Lab at the Department of Pharmacy and Biotechnology of the Università di Bologna (UNIBO), the first Brazil-Bologna joint laboratory dedicated to the development of new drugs for the treatment of Alzheimer's disease. São Paulo Research Foundation Oct 17 2024 A self-proclaimed Brazil-Italy collaboration enthusiast, researcher Laura Bolognesi created the B2AlzD2 Joint [...]

An article published in the journal Brain, Behavior, and Immunity reports the findings of a study by researchers based in Brazil, the United States and South Korea who set out to understand how viral infections cause pain and to contribute to the search for novel ways of relieving it. The article shows that a channel known to mediate pain can be activated when an immune system sensor known as STING (stimulator of interferon genes) recognizes certain nucleic acids, such as viral DNA. STING is a [...]