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A study conducted at the Federal University of São Carlos (UFSCar), in the state of São Paulo, Brazil, shows that tests of functional mobility and muscle strength can be adapted so that they can be performed at home under remote supervision by health professionals, especially for older people with dementia. The telehealth protocol also involves training for caregivers. Tests of functional mobility and muscle strength are widely used by physical therapists and geriatricians to [...]

A study conducted in Brazil points to long-term functional abnormalities in their lungs two years after hospital discharge in most severe COVID-19 patients who had required intubation, and a return of pulmonary lesions after 24 months in some people who appeared to have fully recovered on being discharged. The study involved 237 patients admitted to Hospital das Clínicas, a hospital complex run by the University of São Paulo's Medical School (FM-USP), between March and [...]

Already at the beginning of the COVID-19 pandemic, a group of Brazilian researchers pioneered in showing why SARS-CoV-2 infection tends to be more severe in diabetic patients. Now, the same team based at the Institute of Biology of the State University of Campinas (IB-UNICAMP) has discovered one of the reasons why obese people who do not have diabetes or even insulin resistance also have an increased risk of developing the severe form of the disease. “New experiments show that the [...]

For the first time, researchers have identified a group of neurons deep in the brain that are associated directly with compulsive eating and food craving. The discovery is reported in an article published in Nature Communications by researchers at the University of California, Los Angeles (UCLA) in the United States and the Federal University of the ABC (UFABC) in São Bernardo do Campo, São Paulo state (Brazil).  The neurons are located in the [...]

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that SARS-CoV-2, the virus that causes COVID-19, can remain in the sperm of patients for up to 90 days after hospital discharge and up to 110 days after the initial infection, reducing semen quality. The study is reported in an article published in the journal Andrology. The authors suggest that people who plan to have children should observe a period of “quarantine” after [...]

A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to a Brazilian study reported in the Journal of Medical Virology. The study confirmed the vaccine’s effectiveness and its importance to control of the disease, while also showing that, more than three years after the first application of a COVID-19 vaccine in Brazil, the [...]

The chikungunya virus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes and responsible for more than 900 deaths in Brazil since it arrived around ten years ago, is capable of spreading through the blood, reaching multiple organs and crossing the blood-brain barrier, which protects the central nervous system. The mechanisms of action observed for the first time in fatal cases by a group of Brazilian, American and British researchers are reported in an article published in Cell [...]

Introduction Tuberculosis (TB) is a highly infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body. According to the World Health Organization (WHO), TB is one of the top 10 causes of death worldwide, with an estimated 10 million people falling ill with the disease in 2019 alone. The Study A recent study conducted by University of São Paulo has shed light on a mechanism that aggravates [...]

Research conducted at the University of São Paulo (USP) in Brazil shows that SARS-CoV-2, the virus that causes COVID-19, can infect liver cells (hepatocytes), stimulating glucose production and leading to a condition similar to diabetes (hyperglycemia) in hospitalized patients, even if their blood sugar level was normal before they were admitted to hospital. An article on the study is published in Proceedings of the National Academy of Sciences (PNAS). The findings describe part of [...]