SÃO PAULO – In less than 48 hours after registering the second case of a Brazilian infected with coronavirus, a team of Brazilian researchers was able to sequence the virus’s genome again. They are the same scientists who had done the first sequencing, in a procedure that will become routine for the epidemic. Now it must be faster and faster.
And the new analysis shows that the pathogen in the second case is slightly different from the first. By analysis, the first had more resembled viruses that had been sequenced in Germany. The second is closer to viruses sequenced in England. And both are different from Chinese sequences.
In both cases, however, the patients were infected in Italy, but as Italian scientists have not yet presented the sequencing of the viruses that are in the country, the comparison could not be made with the material there.
According to researcher Ester Sabino, from USP’s Institute of Tropical Medicine, who is part of the sequencing efforts, together with researchers from the Adolfo Lutz Institute and USP’s Faculty of Medicine, these variations confirm that internal transmission between European countries has already is well established.
“The epidemic has been going on for some time in Europe and is already passing from one country to another. But at that moment we still cannot know if she went from China to Germany and England and from there to Italy or if she went to Italy and from there she went to England ”, for example.
She explains that with each passing month the virus undergoes a mutation and gets a kind of code from the region where it passed, showing its path.
The work is part of the Joint Brazil-United Kingdom Center for Discovery, Diagnosis, Genomics and Epidemiology of Arbovirus (Cadde), supported by Fapesp and the Medical Research Centers, from the United Kingdom, which develops new techniques to monitor epidemics in real time and offer clues to answer the problem.