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Human Brain Organoids Reveal How a Genetic Mutation Disrupts Neural Development
Publicado em 03 de maio de 2022
Scientists at the University of California, San Diego (UCSD), School of Medicine used human brain organoids to reveal how a genetic mutation associated with a profound form of autism disrupts neural development. Using gene therapy tools to recover the gene’s function effectively rescued neural structure and function.
Their study is published in Nature Communications, in a paper titled, “ Transcription Factor 4 loss-of-function is associated with deficits in progenitor [...]
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Left-Handed Nanoparticle Adjuvant Boosts Flu Vaccine Efficacy in Mice by 25%
Publicado em 20 abril 2022Vaccines can be made more than 25% more effective by adding left-handed chiral gold nanoparticles as adjuvants, according to the results of a study by an international research team in China, the United States, and Brazil. In a publication in Nature, the researchers reported the results of tests with their nanoparticles on human immune cells and also in combination with a vaccine against the influenza virus. “The key to understanding the contribution of these nanoparticles is the concept [...]ver notícia