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Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids
Publicado em 03 de maio de 2022
Summary: A brain organoid study reveals how a genetic mutation associated with Pitt-Hopkins syndrome, a profound form of autism, disrupts neural development. Using gene-editing technology, researchers recovered the function of the TCF4 gene and effectively restored neural structure and function. Source: UCSD In a study published in Nature Communicationsscientists at the University of California San Diego School of Medicine used human brain organoids to reveal how a genetic [...]